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胸腺肽α_1治疗老年慢性阻塞性肺疾病合并侵袭性肺真霉菌病的临床效果观察 被引量:1

Clinical effect of thymosin α_1 in the treatment of elderly patients with chronic obstructive pulmonary disease complicated with invasive pulmonary fungal infection
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摘要 目的:探讨胸腺肽α_1治疗老年慢性阻塞性肺疾病合并侵袭性肺真霉菌病的疗效。方法:收治老年COPD合并IPA患者37例,随机分成观察组(20例)与对照组(17例),对照组使用常规方法治疗,观察组在此基础上加用胸腺肽α_1治疗。结果:观察组CD4^+、CD4^+/CD8^+升高幅度明显大于对照组,CD8^+下降幅度明显大于对照组(P<0.05)。结论:常规治疗联合胸腺肽α_1治疗老年COPD合并IPA的疗效显著。 Objective:To investigate the efficacy of thymosin α 1 in the treatment of elderly patients with chronic obstructive pulmonary disease complicated with invasive pulmonary fungal ilffection.Methods:37 elderly patients with COPD combined with IPA were randomly divided into the observation group(with 20 cases) and the control group(with 17 cases),the control group were treated with routine method,and the observation group were treated with thymosin α 1 on this basis.Results:The amplitude of CD4+ and CD4+/CD8 in the observation group was significantly higher than that in the control group,and the decrease of CD8 + was significantly larger than that in the control group(P 〈 0.05).Conclusion:Routine treatment combined with thymosin α 1 is effective in the treatment of elderly patients with COPD combined with IPA.
作者 余芳 Yu Fang(Department of Geriatrics,the Traditional Chinese Medicine Hospital of Leshan City 614000)
出处 《中国社区医师》 2018年第28期81-81,88,共2页 Chinese Community Doctors
关键词 胸腺肽Α1 慢性阻塞性肺疾病 侵袭性肺真霉菌病 疗效 Thymosin α 1 Chronic obstructive pulmonary disease(COPD) Invasive pulmonary mycosis Curative effect
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