摘要
目的对某院心血管门诊处方中口服质子泵抑制剂(proton pump inhibitors,PPIs)使用合理性进行评价,为临床合理用药提供参考。方法从某院信息管理系统(hospital information syetem,HIS)抽取2016-01~12月含有口服PPIs的心血管门诊处方共2906份,参照药品说明书、PPIs临床应用指导原则、应激性溃疡预防指南,从用药频率、适应症、用法用量以及联合用药4个方面对口服PPIs使用进行评价。结果 2906份处方中,使用频率前3位的依次是泮托拉唑、兰索拉唑和雷贝拉唑;预防性用药不适宜处方366份(12.60%)。结论该心血管门诊口服PPIs应用相对规范,但仍存在无适应症用药和联合用药不合理现象,药师在调配处方时应注意审核并及时与处方医生沟通。
Objective To investigate rationality of oral proton pump inhibitors（PPIs）in cardiovascular outpatient prescriptions in a hospital,and provide reference for clinical use of PPIs.Methods A total of 2906 prescriptions of oral PPIs were collected from January to December 2016.According to the package insert,guiding principle of clinical application of PPIs and guidelines for stress ulcer prevention,the frequency of utilization,indication,usage and dosage,and drugs combination of PPIs were analyzed.Results Among 2906 prescriptions,the top three PPIs use were pantoprazole,lansoprazole and rabeprazole.A total of 366 prescriptions（12.60%）were unsuitable prophylactic medication.Conclusion The application of oral PPIs in cardiovascular outpatient is relatively normal,but there are some problems such as no indication usage and unreasonable drugs combination.Pharmacists should pay more attention to prescription audit and timely communication with the doctors.
作者
肖庆
黄雪峰
李健
袁进
高洁宜
曾颖
XIAO Qing;HUANG Xuefeng;LI Jian;YUAN Jin;GAO Jieyi;ZENG Ying(Department of Medical Management,Guangzhou General Hospital of Chinese People＇s Liberation Army,Guangzhou Guangdong 510010,China)
出处
《华南国防医学杂志》
CAS
2018年第9期649-653,共5页
Military Medical Journal of South China
基金
广州市科技计划项目(201509010012)
关键词
质子泵抑制剂
心血管门诊
大数据
处方
评价
Proton pump inhibitors
Cardiovascular outpatient
Big data
Prescription
Evaluation
