摘要
采用28日龄SPF鸡,对禽脑脊髓炎油乳剂灭活疫苗及弱毒活疫苗进行了免疫效果评估。抗体检测结果表明,疫苗免疫后21日,油乳剂灭活疫苗免疫组抗体水平及抗体转阳率优于弱毒活疫苗免疫组。攻毒保护试验结果表明,禽脑脊髓炎油乳剂灭活苗及弱毒活疫苗均具有良好的免疫保护性,对禽脑脊髓炎病毒强毒VR株的保护率分别为100%、90%。综上所述,灭活疫苗和活疫苗均可有效预防禽脑脊髓炎。
28-day-old SPF chickens were used to evaluate the immunical efficiency of Avian Encephalomyelitis oil emulsion inactivated vaccine and attenuated live vaccine. The results of antibody detection showed that the antibody titers elicited by the oil emulsion inactivated vaccine were higher than those of the attenuated vaccine at 21 days post immunization. Challenge test results showed that both of the oil emulsion inactivated vaccine and the attenuated live vaccine had good immunity protection, and the protection rates for the virulent VR strain of Avian Encephalomyelitis virus were 100 % and 90 %, respectively. The results showed that both vaccines can be used for prevention and control of Avian Encephalomyelitis.
作者
曾凡桂
刘佳佳
王占新
严专强
鲁俊鹏
Zeng fangui;Liu jiajia;Wang zhanxin;Yan zhuanqiang;Lu junpeng(Guangdong Wen＇s Foodstuffs Group Co.,Ltd,Xinxing 527439,China;Guangdong Provincial Key Laboratory of Healthy Animal Husbandry and Environmental Control,Xinxing 527439,China)
出处
《广东畜牧兽医科技》
2018年第5期46-48,共3页
Guangdong Journal of Animal and Veterinary Science
关键词
禽脑脊髓炎
灭活疫苗
弱毒疫苗
免疫效果
Avian Encephalomyelitis
Inactivated vaccine
Attenuated live vaccine
Immune efficiency
