摘要
目的了解昆明地区患者吸入性过敏原和食物过敏原特异性IgE抗体分布特点,为过敏性疾病防治提供参考。方法以2015年3月～2017年12月在昆明市第一人民医院就诊的1 674例过敏性疾病患者为实验对象。用欧蒙免疫印迹法检测血清过敏原特异性IgE抗体。结果 1 674例过敏性疾病患者中,吸入性过敏原以屋尘螨/粉尘螨检出率最高,食物过敏原以海洋鱼类组合检出率最高。婴幼儿期以食物过敏原过敏为主,随着年龄增长吸入性过敏原逐渐增多,而食物过敏原逐步减少。结论本地区吸入性过敏原以屋尘螨/粉尘螨较常见,食物过敏原以海洋鱼类组合较常见。血清过敏原的检测可为过敏性疾病的病因学诊断、治疗和预防提供帮助。
Objective To analyze the IgE antibody distribution characteristics of the patient＇s specific inhaled allergens and food allergen in KunMing,and to provide a reference for patients allergic disease prevention and control. Methods 1 674 cases of patients with allergic disease in The First Hospital of Kunming from March 2015 to December 2017 were included as objects. The western-blotting method was used to detect specific serum allergen IgE antibody. Results Among the 1674 patients with the allergic disease, inhaled allergens mainly contained house dust mites and dust mites, food allergens mainly consisted of Marine Fishes. In infant and young children period, the food was the main allergic source. Inhalation allergens increase with age, while food allergens gradually decrease. Conclusion House dust mite/dust mite is the most common inhalant allergen,and food allergens are more common in combination with Marine fish in this area.Determine Serum allergen tests can provide better help for etiology diagnosis, treatment and prevention of patient＇s allergic disease.
作者
付兰
杨雪松
黎奇
普加宏
黄莓屏
FU Lan;YANG Xue-song;LI Qi;PU Jia-hong;HUAN Mei-ping(Department of Dermatology,The First Hospital of Kunming,Kunming,Yunnan 650000;Department of Dermatology,Yunnan Provincail Hospital of Traditional Chinese Medicine,Kunming,Yunnan 650000)
出处
《皮肤病与性病》
2018年第5期630-632,共3页
Dermatology and Venereology
关键词
过敏原
免疫印迹法
特异性IGE
过敏性疾病
Allergen
Western - blotting method
Allergen specific IgE
Allergic disease
