摘要
探讨裙带菜多糖对S_(180)荷瘤小鼠红细胞内[Ca^(2+)]的影响,实验共设5组,即裙带菜多糖高、中、低剂量组,阳性对照组(黄芪多糖组),阴性对照组(生理盐水组).分别测定裙带菜多糖对荷瘤小鼠红细胞内[Ca^(2+)]、红细胞膜唾液酸含量,红细胞膜电位,红细胞膜Na^+,K^+-ATPase及Ca^(2+),Mg^(2+)-ATPase活性的影响.结果表明:裙带菜多糖能够降低荷瘤小鼠红细胞内[Ca^(2+)],提高含唾液酸量,升高膜电位及膜表面Na^+,K^+-ATPase和Ca^(2+),Mg^(2+)-ATPase的活性.从而提高荷瘤小鼠红细胞膜功能,增强红细胞免疫功能.
This paper studied on the effects of UPPS on Ca 2＋ content in RBC of S 180 tumor-bearing mice. S 180 tumor-bearing micewere divided into five groups： negative control （normal saline）,positive control （Astragalus polysaccharide）,UPPS high, medium and low dose groups. The effect of Ca 2＋ and sialic acid content, membrane potential, Na ＋, K ＋-ATPase and Ca 2＋ , Mg 2＋ -ATPase activityin RBC of S 180 tumor-bearing mice were studied.The results showed that UPPS could reduce the Ca 2＋ content; enhancesialic acid content. The membrane potential advanced and the Na ＋, K ＋-ATPase and Ca 2＋ ,Mg 2＋ -ATPase activity enhanced. Therefore,the RBC immunity of S 180 tumor-bearing mice was enhanced.
作者
胡扬
成秉辰
王金宏
王昊
王福玲
贾玉翠
郑佩玉
张艳君
杨波
HU Yang;CHENG Bing-chen;WANG Jin-hong;WANG Hao;WANG Fu-ling;JIA Yu-cui;ZHENG Pei-yu;ZHANG Yan-jun;YANG Bo(School of Pharmacy,Harbin University of Commerce,Harbin 150076,China;Harbin Testing Center for Food and Drug,Harbin 150076,China;Research Center onLife Sciences and Environmental Sciences,Harbin University of Commerce,Harbin 150076,China)
出处
《哈尔滨商业大学学报（自然科学版）》
CAS
2018年第5期513-515,536,共4页
Journal of Harbin University of Commerce：Natural Sciences Edition
基金
黑龙江省教育厅科学技术研究项目(No.12521134)
关键词
裙带菜多糖
红细胞
CA2+
Undariapinnatifida polysaccharide
RBC
Ca 2＋
