摘要
目的观察和评价通腑解毒汤内服联合灌肠疗法治疗重症急性胰腺炎的临床疗效。方法患者40例随机分为两组,均采用内科常规治疗,观察组加用通腑解毒汤内服联合灌肠法治疗,两组患者均治疗10 d。比较两组患者腹痛缓解时间、肠鸣音恢复时间、首次排便时间和住院时间;两组患者治疗前后急性生理与慢性健康(APACHEⅡ)评分、血淀粉酶(AMS)、尿淀粉酶(UAMY)、血清脂肪酶(LPS)和C反应蛋白(CRP)水平;两组患者中转手术或ICU人数;临床疗效。结果治疗结束后,观察组患者的腹痛缓解时间、肠鸣音恢复时间、首次排便时间和住院时间均短于对照组患者(P<0.05)。观察组患者APACHEⅡ评分显著低于对照组患者(P<0.05)。观察组患者的AMS、UAMY、LPS和CRP降低幅度大于对照组(P<0.05)。观察组中转手术和ICU人数均少于对照组(P<0.05)。观察组临床总有效率为90.00%,高于对照组的70.00%(P<0.05)。结论通腑解毒汤内服联合灌肠疗法可以缓解重症急性胰腺炎患者临床症状,降低AMS、UAMY、LPS、CRP水平和APACHEⅡ评分,减少并发症发生,从而改善重症急性胰腺炎患者的预后,提高临床疗效。
Objective： To observe and evaluate the clinical efficacy of Tongfu Jiedu Decoction combined with enema on severe acute panereatitis. Methods： 40 cases were divided into two groups. The two groups were treat- ed with routine medical treatment. The observation group was treated with Tongfu Jiedu Decoction combined with enema on the basis of＇ routine medical treatment. Two groups were treated for 10 days. The abdominal pain relief time, the recovery time of bowel sounds,the first defecation time and hospital time were observed and analyzed,as well as APACHE Ⅱ scores and the changes of AMS,UAMY,LPS and CRP before and after treatment;the number of surgery or ICU and clinical efficacy were also recorded. Results： After the treatment,the time of abdominal pain relief, the recovery time of bowel sounds, the time of first defecation and the time of hospitalization in the ob- servation group were shorter than those in the control group,with significant difference（P〈0.05） . The APACHE Ⅱ score of the observation group was significantly lower than that of the control group, and the difference was statisti- cally significant （P〈 0.05）. The decrease of AMS,UAMY,LPS and CRP in the observation group was better than that in the control group;the difference was statistically significant （P〈 0.05）. The number of transferred operations and ICU in the observation group was few than that in the control group. The difference between the two groups was statistically significant （P〈 0.05）. The clinical total effective rate of the observation group was 90.00%, the total ef- fective rate of the control group 70.00% ;the clinical effect of the observation group was better than the control group ,and the clinical curative effect of the two groups was significantly different （P〈 0.05）. Conclusion： Tongfu Jiedu Decoction combined with enema therapy can relieve the clinical symptoms of patients with severe acute pan- creatitis,reduce the level of AMS, UAMY,LPS, CRP and APACHE II,and reduce the incidence of complications, so as to improve the prognosis of severe acute pancreatitis and the clinical efficacy.
作者
奚锦要
朱永钦
朱永苹
林寿宁
罗昭琼
Xi Jinyao;Zhu Yongqin;Zhu Yongping(Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine,Guangxi,Nanning 530011,China.)
出处
《中国中医急症》
2018年第10期1752-1754,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
广西壮族自治区卫生和计划生育委员会科研课题(Z2016221)
关键词
重症急性胰腺炎
通腑解毒汤
灌肠疗法
临床研究
Severe acute panereatitis
Tongfu Jiedu Decoction
Enema therapy
Clinical efficacy
