摘要
山豆根,主产于中国西南部的传统药用植物,是广西道地药材。已报道的化学成分主要有生物碱、多糖、酚性成分、黄酮类化合物,其中生物碱类是目前研究的热点。但是山豆根也含有大量非生物碱类成分,也是其重要的活性成分。文献调研表明,山豆根非生物碱主要包括黄酮类、三萜类和多糖类等。特别是其黄酮类化合物,具有十分广泛的生物活性,在抗菌,抗病毒,抗氧化,抗癌和抗肿瘤方面具有很大的潜力。本文综述了近年来从山豆根中分离得到的非生物碱类化合物及其药理活性,为山豆根非生物碱类化合物的研究和开发利用提供参考。
Sophorae Tonkinensis Radix Et Rhizoma is a traditional medicinal plant in southwest of China and is a traditional medicinal plant in Guangxi. The reported chemical compositions mainly include alkaloids,polysaccharides,phenolic compounds and flavonoids,and alkaloids are the hot spots in the study. But it also contains a large number of non-alkaloid components,which is also an important active ingredient. Literatures research showed that the Sophora tonkinensis contains flavonoids,triterpenoids and polysaccharides. In particular,its flavonoid compounds have a wide range of biological activities,which have great potential in antibacterial,antiviral,anti-oxidatant,and anti-tumor. In this paper,the non-alkaloid compounds and their pharmacological activities are reviewed,which can provide reference for the research and development of nonalkaloids compounds in S. tonkinensis Gagnep.
作者
李秋萍
缪剑华
宋志军
闫炳雄
吴玲玲
李力
LI Qiu-ping;MIAO Jian-hua;SONG Zhi-jun;YAN Bing-xiong;WU Ling-ling;LI Li(Guangxi Medical University,Nanning 530021,China;The National Engineering Laboratory of Southwest Endangered Medicinal Resources Development of Guangxi Medicinal Plant,Nanning 530023,China)
出处
《中国现代中药》
CAS
2018年第9期1169-1178,共10页
Modern Chinese Medicine
基金
国家自然科学基金面上项目(81473309)
药学研究生创新创业暨联合培养基地项目(20170703)
关键词
山豆根
非生物碱
化学成分
活性
Sophora tonkinensis Gagnep
non-alkaloid
chemical constituents
activities
