摘要
目的探讨年龄≥60岁的带状疱疹后遗神经痛患者发病的相关因素,为预防老年带状疱疹后遗神经痛提供临床依据。方法收集我院皮肤科住院患者168例老年带状疱疹作为研究对象,根据是否有后遗神经痛,分为带状疱疹后遗神经痛组(52例)和非带状疱疹后遗神经痛组(116例)。对168例患者治疗康复过程进行临床分析,研究老年带状疱疹发病年龄、就诊时间、是否规范治疗、是否合并有基础疾病等因素与发生后遗神经痛的内在关系。结果与老年带状疱疹后遗神经痛的发病率有显著相关性的主要因素包括:发病年龄大于60岁、就诊时间大于5 d、不规范治疗(单独使用抗病毒、营养神经或调节免疫等治疗手段,未联合治疗2周)和合并有基础疾病(系统性红斑狼疮、糖尿病和恶性肿瘤等)。结论发病年龄大、合并基础疾病带状疱疹患者,一定要及时给予抗病毒、营养神经、调节免疫等联合治疗,达到有效预防老年带状疱疹后遗神经痛的发生、减轻老年带状疱疹患者病痛的目的。
Objective To discuss the related pathogenic factors of post-herpetic neuralgia （PHN） so as to provide basis for prevention. Methods 168 elderly with herpes zoster （HZ） were enrolled and divided, according to the occurrence of PHN, into 2 groups： PHN group （n = 52） and non-PHN group （n = 116）; analysis was made to the clinical data including the treatment and rehabilitation process and the internal relation between PHN and such factors as the onset age of the elderly, visiting time, standard treatment or not, complication with basic diseases or not was studied. Results The main factors of close correlation with the occurrence PHN in the elderly included the onset age over 60, visiting time over 5 days after onset, unstandard treatment （single application of antiviral drugs or neurotrophy or immunoregulation, with no combined treatment for 2 weeks ） and the complication of basic diseases （such as systemic lupus erythematosus, diabetes and malignant tumors）. Conclusions Immediate treatment with combined application of drugs for anti-virus, neurotrophy and immunoregulation can effectively prevent the occurrence of PHN and reduce the sufferings in the elderly of older onset age and basic disease complications.
作者
陈燕
丁小洁
陈星
王理
熊心猜
Chen Yan, Ding Xiaojie, Chen Xin, Wang Li, Xiong Xin-cai(Department of Dermatology, Affiliated Hospital to North Sichuan Medical College, Nanchong City, Sichuan Province, 637000, P. R. China)
出处
《老年医学与保健》
CAS
2018年第5期494-496,共3页
Geriatrics & Health Care
关键词
老年
带状疱疹
后遗神经痛
预防
elderly
herpes zoster （HZ）
post-herpeticneuralgia （PHN）
prevention
