摘要
目的探析青蒿鳖甲汤治疗阴虚内热型系统性红斑狼疮疗效及对Th1/Th2平衡的影响。方法选取我院在2013年1月—2018年5月收治的60例阴虚内热型系统性红斑狼疮患者作为研究对象,将其随机分为对照组和治疗组。对照组30例实施常规西医治疗,治疗组30例在对照组基础上,服用青蒿鳖甲汤。比较两组患者的治疗效果。结果治疗组患者的治疗有效率为96.67%,高于对照组,差异具有统计学意义(P <0.05);对照组IFN-γ水平、Th1/Th2低于治疗组,IL-4水平高于治疗组,差异具有统计学意义(P <0.05)。结论青蒿鳖甲汤治疗阴虚内热型系统性红斑狼疮临床疗效显著,调节细胞因子平衡。
Objective To explore the effect of Artemisia Bijia Decoction on the treatment of systemic lupus erythematosus due to yin defciency and endogenous heat and its efect on Th1/Th2 balance. Methods 60 patients with systemic lupus erythematosus from January 2013 to May 2018 were selected and divided into the control group and the treatment group. 30 cases in the control group were treated with conventional western medicine, and 30 cases in the treatment group were treated with Artemisia. The efects of the two groups were compared. Results The efective rate of the treatment group was 96.67%, which was higher than that of the control group （P〈0.05）. The levels of IFN-γ and Th1/Th2 in the control group were lower than those in the treatment group, while the levels of IL-4 in the control group were higher than those in the treatment group （P〈0.05）. Conclusion Artemisia Bijia decoction is efective in treating systemic lupus erythematosus due to yin defciency and internal heat, regulating the balance of cytokines.
作者
曹向东
CAO Xiangdong(Department of Rheumatology,The First People＇s Hospital of Changshu City,Changshu Jiangsu 215500,China)
出处
《中国继续医学教育》
2018年第30期154-156,共3页
China Continuing Medical Education
关键词
青蒿鳖甲汤
阴虚内热
系统性红斑狼疮
TH1
TH2
影响
Artemisia Bijia decoction
Yin deficiency internal heat
systemic lupus erythematosus
Th1
Th2
infuence
