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^(125)I粒子植入术后辐射防护的最优化研究 被引量:2

A study on the optimization of radiological protection after brachytherapy with radioiodine seeds
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摘要 目的:通过检测自行设计的含铅穿戴用品对125I粒子植入患者的放射性屏蔽效果,优化辐射防护的个体化方法。方法:125I粒子植入患者69例,术后根据粒子植入的部位和数量选择穿戴不同类型的含铅防护用品。术后24小时内检测患者无屏蔽与穿戴不同铅当量屏蔽用品在不同距离的辐射剂量,并按接触时间计算与患者密切接触的病区医务人员(AAED)及陪护人员(AED)所接受的辐射剂量。结果:患者无屏蔽时,在0. 5 m处的医务人员所受的年平均辐射剂量小于放射工作人员限值20 m Sv,在2 m处接近公众限值1 m Sv,在4 m处接近本底;在1 m处的陪护人员所受的平均辐射剂量接近公众限值1 m Sv,在4 m处接近本底。患者穿戴0. 25 mm Pb含铅屏蔽用品时,零距离有58位患者的辐射剂量高于本底,但对医务及陪护人员产生的平均辐射剂量接近公众限值,其中最高者为1. 8 m Sv;穿戴0. 5 mm Pb含铅屏蔽用品时,患者零距离辐射剂量接近本底。结论:125I粒子植入后,患者穿戴0. 25 mm Pb含铅屏蔽用品时,绝大部分(68/69例)患者不会对医务及陪护人员造成辐射损伤;粒子植入数量较多和/或植入部位距体表较近的患者,若穿戴0. 25 mm Pb的屏蔽用品在0. 3 m处辐射剂量大于本底,则应穿戴0. 5 mm Pb的含铅屏蔽用品。 Objective: To optimize the individual radioprotective methods after125 I brachytherapy by detecting the shielding effects of different self-designed lead shields. Methods: Sixty-nine hospitalized patients accepted125 I seeds implantation in the mini-invasive interventional ward of Peking University Shenzhen Hospital were enrolled in this study. Individualized radioactive shields were designed according to different implantation sites and quantities of implanted seeds. Within 24 hours after brachytherapy,the radiation doses represented by equivalent dose rate of the patients without shielding,with 0. 25 mm Pb and 0. 5 mm Pb shielding were detected respectively by an X-γ ray detector at different distances,and the radiation doses of the ward staff and caregivers were calculated according to the close contact time. Results: The average annual equivalent dose( AAED) of the ward staff at 0. 5 m without radioactive shield was less than 20 m Sv,the limit for radioactive staff,and was close to the public limit of 1 m Sv at 2. 0 m,and approached to the background at 4. 0 m. The average equivalent dose( AED) of the caregivers at 1. 0 m without shielding was close to the public limit,and near to the background at 4. 0 m. With 0. 25 mm Pb shielding,58 out of 69 patients' radiation doses at zero distance were higher than the background,and the AAED of the ward staff and AED of the caregivers were close to the public limit,among which the highest was 1. 8 m Sv. With 0. 5 mm Pb shielding,all the patients' radiation doses at zero distance were near to the background. Conclusion: With 0. 25 mm Pb shielding,there will be no radiation damage to the ward staff and caregivers by majority of brachytherapy patients,and 0. 5 mm Pb shield should be used if the patient's radiation dose is higher than the background at 0. 3 m.
作者 吴鸣 邓秀兰 杨红杰 邓小梅 成先义 陈俊辉 胡疏 Wu Ming;Deng Xiulan;Yang Hongjie;Deng Xiaomei;Cheng Xianyi;Chen Junhui;Hu Shu(Department of Mini-invasive Interventional Radiology;Department of Nuclear Medicine,Peking University Shenzhen Hospital,Guang dong Shenzhen 518036,China)
出处 《现代肿瘤医学》 CAS 2018年第22期3637-3641,共5页 Journal of Modern Oncology
基金 深圳市科技计划项目(医疗卫生类)(编号:201302066) 深圳市卫生系统"三名工程""国家分子医学转化科学中心陈志南院士肿瘤介入生物治疗团队"(编号:SZSM201612071)
关键词 碘粒子 近距离放射疗法 辐射防护 最优化 radioiodine seeds braehytherapy radiological protection optimization
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