热疗联合放疗治疗子宫颈癌的临床效果被引量：2

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摘要目的探究对子宫颈癌患者联合应用热疗与放疗两种方法的治疗效果。方法择取2014年8月到2017年8月于我院接受治疗的子宫颈癌患者80例,通过随机摸球法分为试验组与参照组,各40例。对参照组予以放疗,试验组则在此基础上同时予以热疗,对比两组患者的近期疗效以及不良反应的发生情况。结果试验组治疗的近期总有效率为90.00%,显著高于参照组的67.50%,P<0.05,差异具有统计学意义。试验组的不良反应总发生率为37.50%,与参照组的35.00%相比无明显差异,P>0.05,差异无统计学意义。结论对处于中晚期子宫颈癌患者同时予以放疗与热疗能够有效改善治疗效果,且治疗安全性较佳,因此可以将联合疗法推广使用。

作者王瑞芳田晓予

机构地区河南科技大学第一附属医院

出处《内蒙古医学杂志》 2018年第10期1199-1200,共2页 Inner Mongolia Medical Journal

关键词热疗放疗子宫颈癌

分类号 R737.3 [医药卫生—肿瘤]

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1陈燕,陈小刚.化疗与放化疗对Ⅰb-Ⅱa期子宫颈癌术后有危险因素患者预后的影响效果观察[J].中国性科学,2016,25(6):49-52. 被引量：6
2李雷,吴鸣,杨佳欣,万希润,黄惠芳,潘凌亚,沈铿,郎景和,向阳.卵巢上皮性癌和子宫颈癌患者铂类药物超敏反应的临床分析[J].中华妇产科杂志,2016,51(11):825-831. 被引量：16
3杜珂,靳义强,李泉.热疗联合同步放化疗治疗中晚期宫颈癌的临床观察[J].海南医学,2013,24(19):2837-2839. 被引量：4
4沈晓燕,崔恒.复发性和转移性子宫颈癌化疗的研究进展[J].中华妇产科杂志,2013,48(10):788-791. 被引量：11
5王海红.放疗联合热疗治疗中晚期宫颈癌的疗效观察[J].山西医药杂志（下半月）,2013,42(4):420-421. 被引量：1
6王丹,吴鸣,任彤,万希润,冯凤芝,黄惠芳,杨佳欣,沈铿,向阳.化疗前血红蛋白及血小板水平对子宫颈癌新辅助化疗后手术患者化疗疗效及预后的影响[J].中华妇产科杂志,2012,47(8):577-581. 被引量：17
7赵庆文,刁建峰,闻庆,宋利,任云.热疗联合同步放化疗治疗中晚期子宫颈癌的近期效果[J].肿瘤研究与临床,2016,28(8):546-548. 被引量：4
8张文陆,王言,崔慧霞.子宫颈癌放疗同步化疗治疗中顺铂用药临床观察[J].中国医科大学学报,2013,42(12):1087-1090. 被引量：10

二级参考文献90

1Siegel R, Ward E, Brawley O, et al. Cancer statistics, 2011 :the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin,2011,61:212-236.
2Bellati F, Pernice M, Manci N, et al. Hemoglobin variation and blood transfusion rates in patients affected by locally advanced cervical cancer undergoing neo-adjuvant chemotherapy followed by radical surgery: the role of erythropoietic growth factors. Ann 0ncol,2007,18:722-729.
3Harrison L, Blackwell K. Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy? Oncologist ,2004,9 Suppl 5:31-40.
4Salven P, Orpana A, Joensuu H. Leukocytes and platelets of patients with cancer contain high levels of vascular endothelial growth factor. Clin Cancer Res, 1999,5:487-491.
5Grigiene R, Valuckas KP, Aleknavicius E, et al. The value of prognostic factors for uterine cervical cancer patients treated with irradiation alone. BMC Cancer,2007,7:234.
6Ferrandina G, Distefano M, Smaniotto D, et al. Anemia in patients with locally advanced cervical carcinoma administered preoperative radiochemotherapy : association with pathological response to treatment and clinical outcome. Gynecol 0ncol,2006, 103:500-505.
7Hernandez E, Donohue KA, Anderson LL, et al. The significance of thrombocytosis in patients with locally advanced cervical careinoma:a Gynecologic Oncology Group study. Gynecol Onco1,2000,78 : 137-142.
8Fuso L, Mazzola S, Marocco F, et al. Pretreatment serum hemoglobin level as a predictive factor of response to neoadjuvant chemotherapy in patients with locally advanced squamous cervical carcinoma : a preliminary report. Gynecol Oncol,2005,99 (3 Suppl 1) :S187-191.
9Gadducci A, Cosio S, Zola P, et al. Pretreatment platelet and hemoglobin levels are neither predictive nor prognostic variables for patients with locally advanced cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy : a retrospective Italian study. Int J Gynecol Cancer,2010,20:1399-1404.
10Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline ( version 1.1 ). Eur J Cancer,2009,45:228-247.