摘要
目的探讨持续质量改进护理模式在中耳炎患者中运用对患者血清中T细胞亚群及耳积液中炎症介质的影响。方法将本院收治的108例中耳炎患者按照数字表法随机分为2组,各54例。2组患者均给予氨溴索、曲安奈德鼓室内注射治疗。对照组给予常规护理方法,试验组给予持续质量改进护理模式。比较2组患者血清T细胞亚群、耳积液炎性介质、不同频率气导听阈的差异。结果护理4周后、护理8周后试验组CD3、CD4和CD8细胞水平升高,高于同期对照组;护理4周后、护理8周后试验组TNF-α、CRP、IL-10水平降低,低于同期对照组;护理4周后、护理8周后试验组在500 Hz、1 000 Hz、2 000 Hz气导听阈降低,低于同期对照组,上述差异均有统计学意义(P<0.05)。结论持续质量改进护理模式对中耳炎患者临床效果佳,其可改善患者免疫功能及听力功能、降低局部炎症反应,值得临床选择。
Objective To investigate the effect of continuous quality improvement care model on serum T lymphocyte subsets and ear effusion inflammatory mediators in patients with otitis media. Methods 108 cases of otitis media admitted to our hospital were randomly divided into two groups according to the digital chart. Two groups of patients were given ambroxol and triamcinolone acetonide injection,while 54 cases in the control group were treated by routine nursing,and 54 cases in the experimental group were treated with continuous quality improvement nursing mode. The difference between the two groups of patients with serum T cell subsets,ear effusion of inflammatory mediators and different frequency air conduction threshold were compared.Results After 4 weeks and 8 weeks of nursing care,the levels of CD3,CD4 and CD8 cells in the experimental group significantly increased,and were higher than that in the control group. After 4 weeks and 8 weeks of nursing care,the levels of TNF-alpha,CRP,IL-10 in the experimental group significantly decreased,and were lower than that in the control group.After 4 weeks and 8 weeks of nursing care,500 Hz,1 000 Hz,2 000 Hz air conduction threshold in the experimental group significantly decreased,and were lower than that in the control group,with the above differences statistically significant（ P 〈0. 05）. Conclusion The continuous quality improvement nursing model has a good clinical effect on patients with otitis media. It can improve the immune function and hearing function,and reduce the local inflammatory reaction,which is worthy of clinical selection.
作者
刘引弟
谢莉萍
严凤娇
LIU Yin-di;XIE Li-ping;YAN Feng-jiao(The First Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong 510080,China)
出处
《中国卫生检验杂志》
CAS
2018年第18期2267-2269,2272,共4页
Chinese Journal of Health Laboratory Technology
关键词
持续质量改进护理模式
中耳炎
T细胞亚群
炎症介质
Continuous quality improvement care model
Otitis media
T lymphocyte subsets
Inflammatory mediators
