摘要
目的对胃黏膜活检常规HE染色对幽门螺杆菌感染的诊断价值进行研究分析。方法选择2016年7月至2017年7月在我院进行治疗的幽门螺杆菌患者共260例作为研究分析对象,对所有患者进行胃镜检查以及取胃窦组织进行胃黏膜活检常规染色、PCR检测,对幽门螺杆菌感染进行诊断。将PCR以及UBT结果作为标准,对胃黏膜活检常规HE染色的诊断价值进行评估。结果经过PCR以及UBT检查,发现105例阴性、155例阳性,在胃黏膜活检常规HE染色中,发现140例阴性、120例阳性,胃黏膜活检常规HE染色的诊断特异性为75.00%、敏感率为77.42%、准确率为86.54%。结论对幽门螺杆菌感染患者进行常规病理诊断的同时进行感染的诊断,具有一定的临床价值,值得临床推广应用,但是因为敏感性不高,针对与幽门螺杆菌密切的疾病需要进行其他的检查。
Objective To study the diagnostic value of routine HE staining for gastric mucosal biopsy for Helicobacter pylori infection. Methods A total of 260 patients with Helicobacter pylori who were treated in our hospital from July 2016 to July 2017 were enrolled in the study. All patients underwent gastroscopy and gastric mucosal biopsy routine staining and PCR. Detection, diagnosis of Helicobacter pylori infection. The diagnostic value of routine HE staining for gastric mucosal biopsy was evaluated using PCR and UBT results as criteria. Results After PCR and UBT examination, 105 cases were found to be negative and 155 cases were positive. In the routine HE staining of gastric mucosa biopsy, 140 cases were found to be negative and 120 cases were positive. The specificity of conventional HE staining for gastric mucosal biopsy was 75.00%, sensitive. The rate was 77.42% and the accuracy rate was 86.54%. Conclusion The diagnosis of infection in patients with Helicobacter pylori infection has a certain clinical value and is worthy of clinical application. However, because of the low sensitivity, other diseases that are closely related to Helicobacter pylori need to be carried out an examination.
作者
麦海浪
张伟华
杨蕊
MAI Hai-lang;ZHANG Wei-hua;YANG Rui(Xishuangbanna People's Hospital,Xishuangbanna,Yunnan,666100)
出处
《智慧健康》
2018年第22期127-128,共2页
Smart Healthcare
关键词
胃黏膜
活检
幽门螺杆菌感染
Gastric mucosa
Biopsy
Helicobacter pylori infection