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分析阿托伐他汀辅治冠心病对动脉粥样硬化程度的影响

The Effect of Atorvastatin on The Degree of Atherosclerosis in Coronary Heart Disease
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摘要 目的探讨阿托伐他汀辅治冠心病对动脉粥样硬化程度的影响。方法选取2015年1月至2017年6月我院收治的360例冠心病患者为研究对象,随机分为观察组207例和对照组153例,对照组给予常规治疗,观察组在对照组的基础上接受阿托伐他汀辅助治疗,对比两组动脉粥样硬化改善情况和临床指标变化水平。结果两组治疗后各项血脂水平均有所改善(P<0.05);观察组血脂水平改善程度优于对照组(P<0.05);两组治疗后动脉粥样硬化程度改善优于治疗前(P<0.05);观察组治疗后动脉粥样硬化程度优于对照组(P<0.05);观察组治疗总有效律高于对照组(P<0.05);观察组心血管事件发生几率低于对照组(P<0.05)。结论在冠心病患者的治疗中应用阿托伐他汀进行辅助治疗,不仅可以提高临床治疗效果,减少心血管事件的发生几率,还可以稳定患者的血脂指标水平,降低动脉粥样硬化程度,值得应用推广。 Objective To investigate the effect of atorvastatin on coronary artery disease in atherosclerosis.Methods 360 patients with coronary heart disease admitted in our hospital from January 2015 to June 2017 were selected as the subjects.207 cases in the observation group and 153 cases in the control group were random Ly divided into two groups.The control group was given routine treatment,and the observation group was treated with atorvastatin on the basis of the control group.The improvement of atherosclerosis and the change of clinical indexes in the two groups were compared.Results The blood lipid levels of the two groups were improved after treatment(P0.05).The improvement of blood lipid level in the observation group was better than that in the control group(P0.05).The improvement of atherosclerosis in two groups after treatment was better than that before treatment(P0.05),and the degree of atherosclerosis in the observation group was better than that in the control group(P0.05).The total effective rate of the observation group was higher than that of the control group(P0.05),and the incidence of cardiovascular events in the observation group was lower than that in the control group(P0.05).Conclusion The use of atorvastatin in the treatment of patients with coronary heart disease can not only improve the clinical treatment effect,but also stabilize the level of blood lipids and reduce the degree of atherosclerosis.Application promotion.
作者 刘兵厚 李范 LIU Bing-hou;LI Fan(Demian Hospital,Dezhou,Shandong,253000;Dezhou Municiple Hospital,Dezhou,Shandong,253000)
出处 《智慧健康》 2018年第13期43-45,共3页 Smart Healthcare
关键词 阿托伐他汀 冠心病 血脂水平 动脉粥样硬化 Atorvastatin Coronary heart disease Blood lipid levels Atherosclerosis
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