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枸橼酸咖啡因联合新生儿呼吸监护自救仪在早产儿呼吸暂停中的应用 被引量:7

Application of caffeine citrate combined with neonatal respiratory monitoring self-rescue instrument in apnea of prematurity
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摘要 目的 探讨枸橼酸咖啡因联合新生儿呼吸监护自救仪在早产儿原发性呼吸暂停中应用的临床效果.方法 选择本院2017年3月至2018年1月收治的原发性呼吸暂停早产儿120例,随机分为对照组和观察组,各60例.两组均实施枸橼酸咖啡因等相同的综合治疗,对照组给予早产儿的常规护理,观察组在对照组基础上实施新生儿呼吸监护自救仪干预的护理措施,比较枸橼酸咖啡因治疗同时两种护理方法的应用效果.结果 实施枸橼酸咖啡因治疗联合新生儿呼吸监护自救仪干预的措施后,观察组的呼吸暂停发生频率、呼吸暂停持续时间、需给予额外刺激(如弹足底、托背刺激)分别为(3.83±1.82)次/d、(22.76±2.54)s、(45.74±12.85)%均较对照组(5.35±1.23)次/d、(30.68±2.38)s、(66.78±13.56)%明显下降,治疗有效率96.67%明显高于对照组88.33%,差异均有统计学意义(均P<0.05).结论 枸橼酸咖啡因治疗联合新生儿呼吸监护自救仪干预较单纯的枸橼酸咖啡因治疗更能明显减少早产儿呼吸暂停的发生,减轻发作程度,提高治疗原发性呼吸暂停的有效率,改善临床症状,从而提高患儿预后,且新生儿呼吸监护自救仪操作简单方便,无其他明显不良反应,具有一定的临床应用价值. Objective To explore the clinical effect of caffeine citrate combined with neonatal respiratory monitoring self-rescue instrument in the treatment ofapnea of prematurity (AOP).Methods 120 cases of AOP in our hospital from March 2017 to January 2018 were randomly divided into control group and observation group with 60 cases in each group.The two groups were given the same comprehensive treatment such as caffeine citrate,the control group was given routine nursing care for premature infants,and the observation group was given nursing measures based on the neonatal respiratory monitoring self-rescue instrument on the basis of the control group.Compared the application effect of two nursing methods.Results After the treatment of caffeine citrate combined with the intervention based on the neonatal respiratory monitoring self-rescue instrument,the frequency and duration of apnea,and the proportion of patients who needed extra stimulation (such as plantar stimulation,dorsum stimulation) in the observation group were significantly lower than those in the control group[(3.83±1.82)times/day vs.(5.35±1.23) times/day,(22.76±2.54)s vs.(30.68±2.38)s,(45.74±12.85)% vs.(66.78±13.56)%],and the effective rate of the observation group was significantly higher than that of the control group (96.67% vs.88.33%),with statistically significant differences (all P〈0.05).Conclusions The combination of citrate caffeine therapy and neonatal respiratory monitoring self-rescue instrument intervention can significantly reduce the incidence of apnea in preterm infants,reduce the severity of apnea,improve the effective rate of treatment of AOP,improve the clinical symptoms and so as to improve the prognosis of children.The instrument is simple and easy to operate,and has no obvious adverse reactions,so it has certain clinical application value.
作者 梁腊梅 黎清耀 刘经飘 曾秋月 Liang Lamei;Li Qingyao;Liu Jingpiao;Zeng Qiuyue(Neonatology Department,Yangjiang Maternal and Child Health Hospital,Yangjiang 529500,China)
出处 《国际医药卫生导报》 2018年第19期3017-3020,共4页 International Medicine and Health Guidance News
关键词 枸橼酸咖啡因 新生儿呼吸监护自救仪 早产儿 原发性呼吸暂停 Caffeine citrate Neonatal respiratory monitoring self-rescue instrument Premature Apnea of prematurity
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