摘要
目的探究单纯硬膜外血肿致脑疝患者再灌注损伤的临床效果。方法选取本院于2010年6月至2017年5月间收治的188例单纯硬膜外血肿致脑疝患者中有10例患者发生再灌注损伤的病例资料进行回顾性分析。着重分析这10例患者的临床表现及影像学资料,对危险因素进行单因素和非条件Logistie回归分析。结果 10例患者中有5例患者的在术中清除血肿15min～30min内存在再灌注脑损伤,剩余5例患者在术后6h内发生再灌注损伤,且CT/MRI显示血肿压迫区域存在水肿、出血灶,CTP显示局部脑组织超灌注。结论脑疝持续时间过程会导致血肿厚度增大从而增高了脑再灌注损伤的几率,应予以控制性减压手术,可争取血管恢复调节功能的时间,促进预后良好。血管恢复调节功能赢得时间,从而改善患者预后。
Objective To explore the clinical study of reperfusion injury in patients with cerebral hernia caused by simple epidural hematoma. Methods 188 cases of cerebral hernia caused by epidural hematoma in our hospital from June 2010 to May 2017 were retrospectively analyzed,and 10 cases with reperfusion injury. The clinical and imaging data of the 10 patients were analyzed,and the single factor and unconditional Logistie regression analysis of the risk factors were carried out. Results Among 10 patients,5 patients occurred brain ischemia reperfusion injury in 15 minutes ～ 30 minutes with hematoma removal during the operation,the remaining 5 patients occurred reperfusion within 6 hours after operation. CT/MRI showed the presence of edema,hemorrhage and hematoma compression area. CTP showed local brain tissue perfusion ultra. Conclusion The duration of cerebral hernia can increase the thickness of hematoma and increase the probability of cerebral reperfusion injury. Controlled decompression should be performed to restore the time of regulating the function of blood vessels and promote the prognosis. The function of vascular recovery and regulation wins the time,thus improving the prognosis of the patients.
作者
秦兆为
李义游
苏华实
陈洪鑫
卢帆
QIN Zhao-wei(Neurosurgery Department of Puning people＇s Hospital,Puning 515300,China)
出处
《牡丹江医学院学报》
2018年第5期18-20,29,共4页
Journal of Mudanjiang Medical University
关键词
单纯硬膜外血肿
脑疝
再灌注损伤
simple epidural hematoma
cerebral hernia
reperfusion injury
