摘要
目的研究左氧氟沙星注射液治疗老年呼吸道感染患者的有效性及安全性。方法采用随机分组方法将方便选取该院2016年1月—2017年1月内科门诊收治的80例老年呼吸道感染患者分为观察组(左氧氟沙星治疗组)和对照组(头孢呋辛治疗组),每组40例。观察组左氧氟沙星400 mg,1次/d,对照组头孢呋辛1.5 g,1次/d,两组疗程均为7 d。比较两组的临床症状改善时间、临床治疗效果及安全性。结果观察组的临床治愈率显著高于对照组(90.00%>72.50%,χ~2=4.021,P<0.05);观察组的临床症状改善时间显著优于对照组(P<0.05);观察组的临床安全性显著优于对照组(7.50%<25.00%,χ~2=4.501,P<0.05)。结论与头孢呋辛相比,左氧氟沙星治疗老年呼吸道感染的临床效果更好,安全性更高,值得临床推广。
Objective To study the efficacy and safety of levofloxacin injection in the treatment of elderly patients with respiratory tract infection. Methods A total of 80 elderly patients with respiratory infections admitted to the department from January 2016 to January 2017 were convenient selected and randomly divided into observation group （levofloxacin treatment group） and control group （cefuroxime treatment group）, with 40 cases in each group. The observation group was treated with levofloxacin 400 rag,once daily, and the control group was cefuroxime 1.5 g once daily. The course of treatment was 7 days. The clinical symptom improvement time, clinical treatment effect and safety of the two groups were compared. Results The clinical cure rate of the observation group was significantly higher than that of the control group （90.00% 〉72.50% , X^2= 4.021, P〈0.05）. The clinical symptom improvement time of the observation group was significantly better than that of the control group （P〈0.05）. Clinical safety in the observation group was significantly better than the control group （7.50% 〈 25.00%, X^2= 4.501, P〈0.05）. Conclusion Compared with cefuroxime, levofloxacin has a better clinical effect and higher safety in the treatment of elderly respiratory infections, which is worthy of clinical promotion.
作者
张永平
ZHANG Yong-ping(Yunnan University of Finance and Economics Hospital,Kunming,Yunnan Province,650221 China)
出处
《中外医疗》
2018年第28期113-114,117,共3页
China & Foreign Medical Treatment
