摘要
目的探讨电子支气管镜注入盐酸氨溴索支气管肺泡灌洗治疗COPD并肺部感染的效果。方法该次研究的对象为方便选取2016年6月—2017年6月在该院进行医治的慢阻性肺疾病并肺部感染患者120例,对其进行自由分组,其中60例采取常规治疗措施为参照组,余下60例患者采取电子支气管镜注入盐酸氨溴索支气管肺泡灌洗治疗为研究组,对比两组患者在医治过程中所需的住院时间和感染病灶吸收时间,比较两组患者在医治前后的CRP、PCT和WBC水平情况。结果研究组住院时间(11.1±3.3)d、感染病灶吸收时间(8.5±2.5)d;参照组住院时间(17.3±3.4)d、感染病灶吸收时间(12.6±3.7)d,研究组所需的住院时间和感染病灶时间均显著比参照组低,差异有统计学意义(t=1.061 5、 2.190 4,P<0.05)。研究组治疗后CRP(32.70±7.10)mg/L、PCT(0.59±0.25)ng/mL、WBC(7.9±3.1)×109/L;参照组治疗后CRP(55.38±6.49)mg/L、PCT(0.90±0.46)ng/mL、WBC(8.5±2.7)×109/L,研究组患者的CRP、PCT和WBC水平均明显比参照组低,数据差异有统计学意义(t=5.39、7.43、11.04,P<0.05)。结论慢性阻塞性肺疾病并肺部感染患者采取电子气管镜注入盐酸氨溴索支气管肺泡灌洗方法进行医治能够取得显著的治疗效果,使得患者的临床症状得到显著的改善,值得在临床上广泛推荐应用。
Objective To investigate the effect of electron bronchoscopy in the injection of ambroxol hydrochloride bronchoalveolar lavage for COPD and pulmonary infection. Methods The study included 120 patients with chronic obstructive pulmonary disease and pulmonary infection who were treated in the hospital from June 2016 to June 2017. They were freely grouped, and 60 case of them received routine treatment in the reference group, the remaining 60 patients underwent electron bronchoscopy with ambroxol hydrochloride bronchoalveolar lavage as the study group. The hospitalization time and the absorption time of the infected lesions, CRP, PCT and WBC levels before and after in the two groups were compared. Resuits The hospitalization time of the study group was （11.1±3.3）d, the absorption time of the infected lesion was （8.5±2.5）d; the hospitalization time of the reference group was （17.3±3.4）d, and the absorption time of the infected lesion was （12.6±3.7）d. The hospitalization time and infection time were significantly lower than the reference group, the difference was statistically significant （t=1.061 5, 2.190 4, P〈0.05）. The study group received CRP （32.70±7.10）ng/mL, PCT （0.59±0.25）ng/mL, WBC （7.9±3.1）×10^9/L after treatment; CRP（55.38±6.49 mg/ L after treatment in the reference group, PCT（0.90±0.46）ng/mL, WBC （8.5±2.7）×10^9/L, the CRP, PCT and WBC levels of the study group were significantly lower than the reference group, and the difference were significantly different （t=5.39,7.43,11.04,P〈0.05）. Conclusion Patients with chronic obstructive pulmonary disease and pulmonary infection who underwent electronic bronchoscopy with ambroxol hydrochloride bronchoalveolar lavage can achieve significant therapeutic effects, which can significantly improve the clinical symptoms of patients. It is worthy of clinical practice, promotion and application.
作者
李红杰
LI Hong-jie(Department of Respiratory Medicine,Guangrao County People＇s Hospital,Guangrao,Shandong Province,257300 China)
出处
《中外医疗》
2018年第27期21-23,共3页
China & Foreign Medical Treatment
