摘要
目的 :研究和探讨中药复方克癌临对荷肝癌 (H2 2 )小鼠的免疫调节作用。方法 :建立荷实体型肝癌(H2 2 )小鼠模型 ,观察经克癌临治疗对其IL - 2和NK细胞活性的影响。结果 :克癌临能显著提高荷瘤小鼠IL - 2和NK细胞活性 ,且其IL - 2活性及NK细胞活性和模型组或阳性对照组 (5 -Fu组 )比较有非常显著性差异 (p<0 0 0 1)。结论 :克癌临方药可显著提高荷瘤机体的抗肿瘤免疫功能。
Abjective: To observe the effect of immunity regulation of the chinese compound prescription Keailin(KAL) treating hepatocarcinoma 22 solid tumor bearing mice.Methods:The model of hepatocarcinoma 22 solid tumor bearing mice was produced and treaded with KAL.The IL 2 activity and NKC activity were observed.Results:KAL could obviously promote the IL 2 and NKC activity,and the IL 2 activity and the NKC activity were significantly different in comparing with model group and 5 Fu group(p<0 001).Conclusion:KAL could significantly enhance the immunity functionn of tumor bearing mice.
出处
《华西医学》
CAS
2000年第4期477-478,共2页
West China Medical Journal
关键词
克癌临
荷实体型肝癌
NK细胞
白细胞介素-2
给药方法
免疫功能
Keailin(KAL)
Hepatocarcinoma 22 solid tumor bearing mice
Interleukin 2 activity
Natural killer cell activity
