摘要
目的:通过分析某院门、急诊处方中应用中药注射液的基本情况以及存在的问题,总结中药注射液的点评思路,以促进中药注射液的临床合理用药,进一步推动中药临床药学工作的开展。方法:抽取2015年1月-2016年12月某院急诊处方中涉及的常用6种中药注射液("参附注射液"、"红花注射液"、"银杏达莫注射液"、"丹参注射液"、"醒脑静注射液"、"参麦注射液")的处方,门诊处方中涉及的常用2种中药注射液("丹参注射液"、"红花注射液")的处方共计3 281张进行处方点评,分析其用药合理性。结果:共抽取急诊处方2 200张、门诊处方1 081张,平均每张处方用药品种数为2.90(剔除葡萄糖、氯化钠等溶媒,以及维生素B_6、维生素C等药物,平均品种数在5个以下,符合相关规定),平均处方金额为320.14元,其中不合理处方225张,占6.46%。不合理处方主要涉及为临床诊断不完整、联合用药不适宜、重复用药、适应证不适宜、溶媒不适宜、用法用量不适宜、给药途径不适宜。对于发现的疑义处方,进行分析,重点关注中药注射液与西药联用的适宜性、中药注射液两两合用的适宜性、中药注射液重复用药的合理性等。结论:中药注射液的处方点评工作可进一步促进中药临床药学的发展,同时需加强临床医师、临床药师的相关知识培训,最终更好地促进中药注射液的合理用药,提高用药安全性。
OBJECTIVE To investigate and analyze the prescriptions of traditional Chinese medicine( TCM) injections in emergency treatment and outpatient service,improve and ensure the safe and rational use of drugs,promote the development of clinical pharmacy for TCM. METHODS The prescriptions of six commonly used TCM injections( including "Shenfu injection","Safflower injection","Ginkgo Leaf Extract and Dipyridamole Injection","Danshen injection","Xingnaojing injection"and "Shenmai injection") in emergency treatment and two commonly used TCM injections( including"Safflower injection"and"Danshen injection") in outpatient treatment from 2015 January to of 2016 December were extracted and analyzed. RESULTS Totally 225 unreasonable prescriptions were found in 3 281 prescriptions,accounting for 6. 46%. Average number of prescription species was 2. 90 and average expenditure of prescription was 320. 14 yuan. CONCLUSION In order to promote the rational drug use in clinical practice and enhance the medication security,the clinicians still need to strengthen their relevant consciousness in the selection of drugs and to participate more training for TCM injections.
作者
马诗瑜
杨婉花
徐培红
MA Shi-yu;YANG Wan-hua;XU Pei-hong(Department of Pharmacy,Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200025,China)
出处
《中国医院药学杂志》
CAS
北大核心
2018年第17期1850-1855,共6页
Chinese Journal of Hospital Pharmacy