摘要
目的通过对沈阳市2016年新发现艾滋病病毒感染者/艾滋病患者(HIV/AIDS)首次外周血T淋巴细胞亚群的检测,了解并估计患者的免疫状况和疾病进展情况。方法采集患者全血样本,用流式细胞仪进行CD4^+T淋巴细胞检测,统计分析检测数据。结果 2016年,沈阳市新发现并检测CD4^+T淋巴细胞的患者共348例。首次检测CD4^+细胞计数平均值为(403. 87±224. 89)个/μl,42. 5%的患者CD4^+细胞≤350个/μl,年龄对CD4^+T淋巴细胞计数影响最大。结论本市HIV感染者的首次检测CD4^+细胞计数较高,但存在大量的长期感染者。建议平时加强HIV相关知识的宣传力度,扩大HIV检测范围,做到早发现、早管理、早治疗,保证新发现患者能够及时检测CD4^+细胞数量,把握治疗时机,更好地防控疾病。
Objective To examine the immunity level and disease progression through the first detection of T lymphocyte subset in newly detected HIV/AIDS cases from Shenyang in 2016. Methods Whole blood samples were taken. Flow cytometry was applied to detect CD4^＋ T lymphocyte, and detection data were statistically analyzed. Results There were 348 HIV/AIDS cases detected and tested for CD4 ^＋ T lymphocyte for the first time. The mean value of CD4^＋ T lymphocyte of the subjects was （403.87 ± 224.89） cells/μl. CD4^＋ T lymphocyte count of 42.5% cases was no more than 350 cells/μl. Age had the greatest influence on CD^＋ T lymphocyte test results. Conclusion CD4^＋ T lymphocyte level is relatively high in the first detection for HIV patients, most of the newly detected HIV/AIDS cases are long - term HIV - infected in Shenyang. It is recommended to strengthen the HIV - related knowledge, expand the HIV testing scope, so as to achieve early detection, early control, and early treatment to ensure the detection of CD4^＋cell counts in newly discovered cases, grasp the timing of treatment, and better prevent and control the infections.
作者
刘建敏
董雪
刘娜
李欣
王琪
LIU Jian-min;DONG Xue;LIU Na;LI Xin;WANG Qi(Shenyang Center for Disease Control and Prevention,Shenyang,Liaoning 110031,China)
出处
《中国卫生检验杂志》
CAS
2018年第20期2493-2495,2498,共4页
Chinese Journal of Health Laboratory Technology
关键词
新发现HIV感染者
艾滋病
CD4^+T淋巴细胞
分析
Newly detected HIV/AIDS cases
Acquired immune deficiency syndrome
CD4 ／^＋T lymphocytes
Analysis
