摘要
目的:探讨组织因子(tissue factor,TF)、组织因子途径抑制物(tissue factor pathway inhibitor,TFPI)在胎盘早剥产妇中的表达水平及临床意义。方法:选择72例胎盘早剥产妇作为观察组,选择73例正常足月产妇作为对照组,均检测TF、TFPI水平,比较两组产妇的TF、TFPI表达水平。结果:观察组母血及脐血中TF水平[(89. 23±22. 18) ng/mg、(97. 23±28. 56) ng/mg]均高于对照组[(67. 45±10. 25) ng/mg、(63. 12±7. 13) ng/mg](P <0. 05);观察组母血及脐血中TFPI水平[(18. 25±7. 26) ng/mg、(19. 23±7. 58) ng/mg]均低于对照组[(26. 89±7. 16) ng/mg、(24. 23±7. 01) ng/mg](P <0. 05)。结论:TF、TFPI是体内重要的凝血及抗凝血因子,母血及脐血中TF、TFPI水平可作为胎盘早剥的参考指标。
Objective： To explore the expression levels and clinical significance of tissue factors （TF） and tissue factor pathway inhibitors （TFPI） in placental abruption parturients. Methods： 72 placental abruption parturients were selected as the observation group and 73 normal full-term parturients were selected as the control group, with the levels of TF and TFPI detected, and the expression levels of TF and TFPI in the two groups compared. Results： The levels of TF in maternal and umbilical blood of the observation group（89.23±22.18, 97.23±28.56）were higher than those of the control group（67.45±10.25, 63.12±7.13）（ P 〈0.05）. The levels of TFPI in maternal and umbilical blood of the observation group（18.25±7.26, 19.23±7.58）were lower than those of the control group（26.89±7.16、24.23±7.01）（ P 〈0.05）. Conclusion： TF and TFPI are important coagulation and anticoagulant factors in the body. The levels of TF and TFPI in maternal blood and umbilical cord blood can be used as the reference indexes for early placental abruption.
作者
康健明
钟颖芙
KANG Jianming;ZHONG Yingfu(Zhanjiang Maternal and Child Health Care and Family Planning Service Center,Guangdong Zhanjiang 524500,China)
出处
《包头医学院学报》
CAS
2018年第10期80-81,共2页
Journal of Baotou Medical College
关键词
胎盘早剥
组织因子
组织因子途径抑制物
表达水平
Placental abruption
Tissue factor
Tissue factor pathway inhibitor
Expression level
