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曲美他嗪联合阿托伐他汀治疗慢性稳定性冠心病效果研究 被引量:5

Research on the Effect of Trimetazidine Combined with Atorvastatin in the Treatment of Chronic Stable Coronary Heart Disease
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摘要 目的:研究曲美他嗪联合阿托伐他汀治疗慢性稳定性冠心病的效果。方法:选择慢性稳定性冠心病患者128例随机分为对照组和研究组各64例。对照组给予阿托伐他汀钙片,研究组在对照组基础上口服盐酸曲美他嗪片。评价两组疗效,观察治疗期间不良反应,治疗前后比较两组心绞痛发作发作频率、持续时间及血液流变学指标。结果:研究组总有效率为95. 3%,对照组总有效率为84. 4%,研究组总有效率高于对照组;治疗后心绞痛发作持续时间于对照组,发作频率显著低于对照组;血液流变学指标低于对照组;差异均有统计学意义(P <0. 05);两组不良反应差异无统计学意义(P> 0. 05)。结论:曲美他嗪联合阿托伐他汀治疗慢性稳定性冠心病效果显著,可显著缩短心绞痛持续时间,减少发作频率,降低血液黏度,且安全性佳。
作者 张帆
出处 《山西职工医学院学报》 CAS 2018年第5期64-66,共3页 Journal of Shanxi Medical College for Continuing Education
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