摘要
目的分析加巴喷丁联合依帕司他治疗糖尿病痛性神经病变(DPN)的临床疗效。方法选择本院于2015年5月—2018年5月收治的48例DPN患者作为研究对象。将其随机分为A组与B组,每组各24例患者。A组给予加巴喷丁+依帕司他治疗,B组给予加巴喷丁单纯治疗。对比整体疗效。结果 A组的治疗总有效率为91.67%,B组为66.67%,组间比较,差异具有统计学意义(P <0.05)。治疗后,两组患者的VAS评分均有所降低,且A组低于B组,组间比较,差异具有统计学意义(P <0.05)。A组的不良反应发生率为20.83%,B组为12.50%,组间比较,差异不具有统计学意义(P> 0.05)。结论为DPN患者行加巴喷丁+依帕司他治疗可减轻疼痛症状,减少不良反应,具有较佳的治疗效果。
Objective To analyze the clinical efficacy of gabapentin combined with elaphim in the treatment of diabetic painful neuropathy （DPN）. Methods 48 patients with DPN admitted in our hospital from May 2015 to May 2018 were selected as the research subjects. They were randomly divided into A group and B group, 24 cases in each group. Group A was given gabapentin plus apapride. Group B was given gabapentin alone. The overall effcacy of two groups was compared. Results The total effective rate of group A was 91.67%, while that of group B was 66.67%, the difference was statistically signifcant （P 〈 0.05）. After treatment, the VAS scores of the two groups were reduced, and the A group was lower than that of the B group, the difference was statistically significant （P 〈 0.05）. The incidence of adverse reactions in group A was 20.83%, and that in group B was 12.50%, the difference was not statistically signifcant （P 〉 0.05）. Conclusion Gabapentin plus DPN is effective in relieving pain symptoms and reducing adverse reactions.
作者
吴卫泽
WU Weize(Department of Internal Medicine,Yixing City Second People＇sHospital,Yixing Jiangsu 214221,China)
出处
《中国继续医学教育》
2018年第32期121-123,共3页
China Continuing Medical Education
