摘要
目的分析心血管疾病患者住院期间急性痛风发作的诱因及治疗效果。方法回顾性分析65例心血管疾病患者住院期间发生急性痛风的临床资料。结果心血管疾病并发急性痛风多见于老年患者和男性,96.9%的患者既往有痛风发作史,住院期间急性发作时76.9%的患者血尿酸水平升高。本组患者中合并高血压48例(73.8%)、心力衰竭34例(52.3%)、冠心病26例(40.0%)。住院期间使用阿司匹林31例(47.7%),使用利尿剂23例(35.4%)。痛风急性发作后改用其他抗血小板药,暂停利尿剂,并给予口服非甾体类抗炎药、秋水仙碱等抗痛风药物治疗2～13d后,患者症状均消失。结论既往有痛风发作史的心血管疾病患者,相关药物治疗可能诱发痛风急性发作,需要采取积极有效的治疗。
Objective To analyze the factors inducing acute attack of gout in the patients with cardiovascular diseases during hospitalization and therapeutic efficacy.Methods Clinical data of 65 patients with cardiovascular diseases suffered from acute attack of gout during hospitalization were retrospectively analyzed.Results The patients with cardiovascular diseases complicated with acute attack of gout were mostly aged and male.The gout attack history was found in 63 cases（96.9%）and 50 cases（76.9%）were suffered from an increased level of blood uric acid.Of 65 patients,48 cases（73.8%）were with hypertension,34 cases（52.3%）with heart failure and 26 cases（40.0%）with coronary heart disease.Aspirin and diuretic were respectively administered in 31 cases（47.7%）and 23 cases（35.4%）.The treatments included the use of other kind of antiplatelet drug instead of aspirin,suspension of diuretics,and orally taking nonsteroid antiinflammatory drugs and antigout drugs（such as colchicine）for 2 to 13 days.The symptoms of gout were all disappeared after treatments.Conclusion The acute attack of gout during hospitalization may be induced by pharmacotherapy in the patients with cardiovascular diseases,who have the history of gout attack.The effective treatments should be taken timely when gout attack happens.
作者
卢小媚
蔡伟
李新
袁斌斌
LU Xiaomei;CAI Wei;LI Xin(Department of Cardiovascular Medicine,BenQ Medical Center,The Affiliated BenQ Hospital of Nanjing Medical University,Nanjing 210019,CHINA)
出处
《江苏医药》
CAS
2018年第10期1121-1124,共4页
Jiangsu Medical Journal
关键词
心血管疾病
痛风
Cardiovascular disease
Gout
