摘要
目的分析四川省2012-2016年麻疹病例的临床症状特征。方法通过全国麻疹监测信息系统收集2012-2016年实验室确诊麻疹病例,对临床症状特征进行描述性流行病学分析。结果在2012-2016年4 092例实验室确诊麻疹病例中,出疹4 015例(98.12%)、发热3 991例(97.53%)、咳嗽3 687例(90.10%)、结膜炎2 627例(64.20%)、卡他2 323例(56.77%)和柯氏斑1 924例(47.02%);咳嗽、卡他和结膜炎同时存在1 715例(41.91%);合并肺炎和/或腹泻1 076例(26.30%)。出疹、卡他症状随年龄增加而减少;有含麻疹成分疫苗(MCV)接种史病例的临床症状少。结论麻疹病例的临床症状多不典型,并受年龄和接种MCV的影响。应加强实验室监测以及时发现麻疹病例。
Objective To describe clinical symptoms of measles cases reported in Sichuan province during 2012-2016. Methods We obtained information on laboratory-confirmed measles cases reported in 2012-2016 to the National Measles Surveillance System and conducted a descriptive analysis of the clinical symptoms. Results Among 4 092 laboratory-confirmed measles cases during 2012-2016, 4 015(98.12%), 3 991(97.53%), 3 687(90.10%), 2 627(64.20%), 2 323(56.77%), and 1 924(47.02%) had rash, fever, cough, conjunctivitis, catarrh, and Koplik spots, respectively; 1 715(41.91%) had a combination of cough, catarrh, and conjunctivitis; 1 076(26.30%) had pneumonia and/or diarrhea. Rash and catarrh decreased with increased age. Persons with measles who previously received measles-contained vaccines(MCV) had fewer symptoms. Conclusions Measles symptoms were often not typical and were influenced by age and MCV vaccination. Laboratory-supported surveillance should be enhanced for timely identification of measles cases.
作者
刘家洁
漆琪
刘宇
李银乔
陈筱纯
Liu Jiajie;Qi Qi;Liu Yu;Li Yinqiao;Chen Xiaochun(Sichuan Provincial Center for Disease Control and Prevention,Chengdu 610041,Sichu,an,China)
出处
《中国疫苗和免疫》
北大核心
2018年第5期517-520,共4页
Chinese Journal of Vaccines and Immunization
关键词
麻疹
临床症状
监测
Measles
Clinical symptom
Surveillance