摘要
目的比较加巴喷丁与卡马西平治疗三又神经痛的临床效果。方法收集20152018年丹东市中心医院收治的三叉神经痛患者77例，随机分为观察组39例与对照组38例。观察组采用加巴喷丁治疗，对照组采用卡马西平治疗，两组均治疗8周。比较治疗前后两组疼痛评分（数字疼痛评分量表，NRS）和生活质量评分（简氏健康相关生活质量问卷-36，SF-36）。结果两组治疗2周、4周、6NNRS评分差异有统计学意义（P〈0.05）。两组治疗8周后SF-36各条目评分差异均有统计学意义（P〈0．05）。结论加巴喷丁治疗三叉神经痛在疼痛控制方面和生活质量改善方面均优于卡马西平，可作为治疗首选。
Objective To compare the clinical effects of gabapentin and carbamazepine in the treatment of trigeminal neuralgia. Methods A total of 77 patients with trigeminal neuralgia admitted to our hospital from 2015 to 2018 were randomly divided into observation group （39 eases） and control group （38 cases）. The observation group was treated with gabapentin, while the control group was treated with carbamazepine. The two groups were treated for 8 weeks. The pain scores （Numeric Rating Scales, NRS） and quality of life score （Jane＇s Health-related Quality of Life Questionnaire-36, SF-36） were compared between two groups before and after the treatment. Results There were significant differences in the NRS scores between two groups at 2 weeks, 4 weeks, and 6 weeks （P〈0.05）. After 8 weeks of treatment, the scores of each item in SF-36 were significantly different between two groups （P〈0.05）. Conclusion Gabapentin is better than carbamazepine in pain control and quality of life improvement for treating trigeminal neuralgia, and can be as the first choice for treatment.
作者
王润龄
WANG Runling(No.4 Department of Neurology, Dandong Central Hospital, Dandong 118002, Liaoning Province, China)
出处
《中国实用乡村医生杂志》
2018年第10期65-67,共3页
Chinese Practical Journal of Rural Doctor
