摘要
目的:探讨盐酸米诺环素联合vitapex根管填充治疗对瘘道型慢性根尖周炎的临床疗效。方法:选取2016年1月—2018年1月就诊于我院口腔科门诊明确诊断为瘘道型慢性根尖周炎患者160例,根据不同根管填充治疗分成对照组(氧化锌丁香油糊剂联合盐酸米诺环素组,n=80)与观察组(vitapex糊剂联合盐酸米诺环素组,n=80),对比两种根管填充情况、牙周相关指标、临床疗效及不良反应的异同。结果:(1)与对照组比较,观察组根管填充出现超填、欠填的比例均明显降低,而适填的比例明显升高(均P <0. 05);(2)治疗后两组患者牙周相关指标(PLI、GI、PD、BI)均明显降低,且治疗后观察组PLI、GI、PD、BI均较对照组明显降低(均P <0. 05);(3)对照组总有效率为75. 0%,观察组为92. 5%,两组比较差异有统计学意义(P=0. 011);(4)与对照组比较,观察组不良反应发生率明显降低(P <0. 01)。结论:盐酸米诺环素联合vitapex根管填充治疗对瘘道型慢性根尖周炎的总体有效率较传统根管治疗更高,不良反应发生率更低,值得临床推广。
Objective：To observe the clinical efficacy of minocycline hydrochloride combined with vitapex root canal filling in the treatment of chronic periapical periodontitis with fistula. Methods：There were 160 patients with chronic periapical periodontitis with fistula who were diagnosed in the department of stomatology of the second hospital of sanming city from January 2016 to January 2018 were selected for the study. There were divided into the control group（ minocycline hydrochloride combined with Zinc oxide clove oil pasteroot canal filling, n = 80 ） and the observation group （minocycline hydrochloride combined with vitapex root canal filling） according to the different root canal filling treatment, contrast the differences of root canal filling conditions, clinical curative effect and adverse reactions between the two group. Results ： （ 1 ） Compared with the control group, the proper filling rate of the observation group was 88.75% , which was higher than that of the control group （65.0%） , the difference was statistically significant（ P 〈 0.05 ）. （2）After the treatment, the levels of PLI, GI, PD, BI in the two groups were significantly decreased ; and the levels of PLI, GI, PD, BI in the observation group after the treatment were significantly lower than the control group （ all P 〈 0.05 ）. （ 3 ） The total effective rate of the observation group was 92.5 %, which was significantly higher than that of the control group（75.0% ）, the difference was statistically significant（ P = 0.011 ）. （4）Compared with the control group, the incidence of adverse reactions was significantly decreased（ P 〈 0.01 ）. Conclusion：The total effective rate of the observation group was significantly higher and the incidence of adverse reactions was significantly lower, which is worthy of clinical promotion.
作者
郑荣焕
林德胜
ZHENG Ronghuan;LIN Desheng(Department of Stomatology,the Second Hospital of Sanming City,Yong＇an City,Fujian Province 36600)
出处
《医学理论与实践》
2018年第21期3177-3179,共3页
The Journal of Medical Theory and Practice
关键词
慢性根尖周炎
根管治疗
VITAPEX糊剂
盐酸米诺环素
Chronic periapical periodontitis
Fistula
Root canal therapy
vitapex paste
Minocycline hydrochloride
