摘要
目的利用动态X线技术分析正常志愿者C4、C5椎体在颈椎屈伸运动过程中的相对位置特征。方法本研究采集2014年10月于我院进行健康查体,无颈椎病病史及X线平片正常的志愿者共22例行颈椎动态X线检查。将受检者分组为低风险组(<40岁)13例,高风险组(≥40岁)9例。经过训练后,利用岛津数字胃肠机对每位受检者颈椎由过屈至过伸位活动的全程进行连续动态摄影,按运动时间顺序存储为DICOM图像。利用Matlab誖2014b软件对每位受检者的整套图像逐帧编程分析,以C6椎体前缘和下缘的交点为基点将同一受检者的所有图像配准,取C4、C5椎前缘和上缘的交点为兴趣点,自动求兴趣点和基准点连线与设定的中垂线的夹角并求差值,反映C4、C5椎体间相对位置的变化。将每例颈椎的运动过程等比分为20个部分,分别计算每部分中位置变化的均值,行重复测量的方差分析检验。所有数据使用SPSS22.0进行统计。结果比较所有受检者颈椎屈伸运动处于不同阶段时,C4、C5椎体的相对位置具有相关性(P<0.001),且C4、C5相对位置变化的差异具有统计学意义(F=16.185,P<0.001)。低风险组和高风险组受检者C4和C5椎体相对位置变化差异具有统计学意义(P=0.019)。采用一元七次方曲线对正常志愿者颈椎屈伸运动过程中C4、C5椎体相对位置变化特征的拟合度最好(P=0.934)。结论无颈椎病正常志愿者颈椎屈伸运动过程中C4、C5椎体相对位置随着颈椎整体运动发生规律性变化,其特征可用一元七次方程拟合;不同年龄人群中C4、C5椎体相对位置变化有差异,超过40岁人群活动度减小。
Objective To analyze the relative position changes of C4 and C5 in normal volunteers during the flexion to extension motion of cervical spine on dynamic radiography. Methods 22 volunteers without cervical spondylosis symptoms and radiographic signs underwent dynamic radiography. They were divided into the low-risk （13 subjects 〈40 years of age） and high-risk （9 subjects ≥ 40 years） groups. The flexion to extension motion was divided into 20 equal parts according to time. The intersection of anterior and inferior edges of C6 was used for all dynamic image registration. The angles formed by intersection of anterior and superior edges of C4 ＆ C5 vertebral bodies were calculated on Matlab. Statistical analysis was performed using repeated measurement ANOVA. Results During flexion to extension motion, the relative positions of C4 and C5 were correlated （P〈0.001） and the relative position changes were significantly different （F=16.185, P〈0.001）. The difference of average relative angles of C4/5 between low risk and high risk groups was statistically significant （F=6.573, P=0.019）. A seven-degree equation was the best curve fit （P=0.934）. Conclusion The C4 and C5 flexion-to-extension position change of healthy adults has a regular pattern that can be described by a seven-degree equation. The position change is reduced in adults older than 40 years of age.
作者
罗嗣频
裴欣欣
王学民
万业达
于锴
何岸苇
LUO Si-pin;PEI Xin-xin;WANG Xue-min;WAN Ye-da;YU Kai;HE An-wei(Department of Radiology,Tianjin Hospital,Tianjin 300211,China)
出处
《影像诊断与介入放射学》
2018年第5期343-348,共6页
Diagnostic Imaging & Interventional Radiology
基金
天津市卫生计生委科研基金资助课题(2011KY23)
关键词
动态X线
颈椎运动范围
图像配准
颈椎退行性骨关节病
颈椎相对位置
曲线拟合
Dynamic X-ray
Cervical spine motion range
Image registration
Cervical spondylosis
Relative position of cervical vertebrae
Curve fitting
