摘要
目的研究分析艾司奥美拉唑与奥美拉唑治疗胃溃疡的临床治疗效果。方法将我院2017年6月至2018年2月收治的80例胃溃疡患者作为本次的研究对象。全部患者随机分为对照组和观察组,每组患者各40例,全部选择口服给药,对比分析两组患者用药后的症状消失情况,胃镜结果及不良反应情况。结果经过45天的治疗,对照组患者的总有效率90%,观察组患者的总有效率为97.5%,两组患者的比较差异有统计学意义(P<0.05)。两组患者用药后,对照组患者发生不良反应的比例为14.7%,观察组患者发生不良反应的比例为2.94%,观察不良反应发生率明显要比对照组低,差异具有统计学意义,P<0.05。结论在治疗胃溃疡时,艾司奥美拉唑(耐信)治疗效果要明显好于奥美拉唑(奥克),不良反应少,为了提高治疗效果,在患者经济条件允许的情况下尽量选择使用艾司奥美拉唑。
Objective to study and analyze clinical effect of o esomeprazole and omeprazole in treatment of gastric ulcer. Methods treat 80 cases gastric ulcer patients admitted in our hospital from June 2017 to February 2018 as study objects. Divide them into control and observation group randomly, 40 cases in each. All patients were treated with oral administration. Compare and analyze symptoms disappearance, gastroscope results and adverse reaction of two groups. Results after 45 days of treatment, total effective rate of control group was 90%, that of observation group was 97.5%, difference showed statistical significance between two groups,（P〈0.05）. After administration of two groups, adverse reactions rate of control group was 14.7%, that of observation group was 2.94%, adverse reaction incidence of observation group was significantly lower than control group（P〈0.05）, difference showed statistical significance. Conclusion esomeprazole（nexium） has better effect in treatment of gastric ulcer than omeprazole（Losec）, the former therapy has less adverse reactions. To improve curative effect, esomeprazole is preferred if patient＇s economic conditions permit.
作者
孙西龙
SUN Xi-long(Department of Gastroenterology,Xuzhou City Central Hospital,Xuzhou,Jiangsu,221000)
出处
《智慧健康》
2018年第12期80-81,共2页
Smart Healthcare
