摘要
目的:探讨紫草乳膏中药材提取工艺的优选方法。方法:采用分光光度法测定羟基萘醌总色素含量,采用高效液相色谱法(HPLC)测定羟基红花黄素A含量,以此作为评价指标,进行正交试验,优选药材提取工艺。结果:紫草、白芷的提取工艺为饮片粗粉加乙醇4倍量浸渍48 h后开始渗漉,溶剂用量为10倍;红花、当归的提取工艺为饮片用水浸泡0. 5 h后,70℃温浸2次,60 min/次,第1次用水12倍量,第2次用水10倍量。结论:紫草乳膏提取工艺合理可行,为紫草乳膏的成型工艺研究及质量控制奠定基础。
Objective：To optimize the extraction process of Zicao cream. Methods：The contents of total pigment of hydroxynaph- thalene were determined by spectrophotometry, and hydroxysafflor yellow A was determined by HPLC. The contents of total pigment of hydroxynaphthalene and hydroxysafflor yellow A were used as the indices for evaluation. Orthogonal test was applied to optinfize the extraction process. Results ：The extraction process of Arnebiae Radix and Angelicae Dahuricae Radix were found to be soaked with 95% alcohol for 48 h using coarse powders, and then percolated with 10 times amount of 95% alcohol; The extraction process of Carthanfi Flos and Angelicae Sinensis Radix were found to be soaked with water for 30 nfin,and then extracted by warm maceration at 70℃ with 12 times amount of water at the first time and 10 times amount of water at the second time, 60 nfin each time. Conclusion ：The process is reasonable and feasible, and lays a foundation for the formation technology of Zicao cream and its quality standards.
作者
曾祖平
石佳
王子君
王宏
Zeng Zuping;Shi Jia;Wang Zijun;Wang Hong(Beijing Institute of Traditional Chinese Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;Capital Medical University,Beijing 100013,China;Hubei University of Chinese Medicine,Wuhan 430065,China)
出处
《世界中医药》
CAS
2018年第11期2872-2875,共4页
World Chinese Medicine
基金
北京中医药科技发展资金项目(JJ2016-03)
