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甲泼尼龙琥珀酸钠联合球蛋白治疗重症手足口病 被引量:2

Methylprednisolone Sodium Succinate Combined With Globulin in the Treatment of Severe Hand Foot Mouth Disease
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摘要 目的探析甲泼尼龙琥珀酸钠联合人免疫球蛋白治疗重症手足口病治疗效果。方法选取我院2015年1月—2018年1月收治的38例重症手足口病患儿作为研究对象。将其随机分为实验组与对照组,每组各19例。对照组施常规甲泼尼龙琥珀酸钠治疗,实验组施甲泼尼龙琥珀酸钠联合人免疫球蛋白治疗,对比分析两组治疗效果及临床指标情况。结果实验组治疗效果较对照组更为显著,差异具有统计学意义(P <0.05);实验组临床指标情况优于对照组,差异具有统计学意义(P <0.05)。结论甲泼尼龙琥珀酸钠联合人免疫球蛋白治疗重症手足口病具有退热快、肢体抖动时间短、安全性高等优点。 Objective To investigate the efficacy of methylprednisolone sodium succinate combined with human immunoglobulin in the treatment of severe hand-foot-mouth disease. Methods 38 severe HFMD patients admitted to our hospital from January 2015 to January 2018 were selected as the research subjects. They were randomly divided into experimental group and control group, 19 cases in each group. The control group was treated with methylprednisolone sodium succinate. The experimental group was treated with methylprednisolone sodium succinate combined with Human Immunoglobulin. The therapeutic effects and clinical indicators of the two groups were compared and analyzed. Results The therapeutic effect of the experimental group was more significant than that of the control group (P〈0.05). The clinical indicators of the experimental group were better than the control group (P〈0.05). Conclusion Methylprednisolone sodium succinate combined with human immunoglobulin for the treatment of severe hand-foot-and-mouth disease has the advantages of rapid fever, short limb vibration time, high safety, etc., and has clinical signifcance in the clinic.
作者 蒲荣玲 赖永艺 陈娟 PU Rongling;LAI Yongyi;CHEN Juan(Department of Pediatrics,Yunfu City People's Hospital,Yunfu Guangdong 527300,China)
出处 《中国继续医学教育》 2018年第33期143-145,共3页 China Continuing Medical Education
关键词 甲泼尼龙琥珀酸钠 人免疫球蛋白 重症手足口病 发热持续 肢体持续抖动 皮疹持续 methylprednisolone sodium succinate human immunoglobulin severe hand foot mouth disease persistent fever persistent limb shaking persistent rash
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