摘要
目的探讨妊娠高血压综合征与极低、超低出生体质量儿合并疾病的关系。方法选取336例极低、超低出生体质量儿,按照孕妇是否有妊娠高血压分为妊高征组和非妊高征组。比较2组患儿一般情况、住院期间主要合并疾病的发生情况。结果共纳入291例,其中妊高征组84例,无妊高征组207例。2组患儿胎龄、剖宫产、母亲年龄、5 min Apgar评分、小于胎龄儿差异有统计学意义(P <0. 05)。2组患儿败血症、颅内出血、支气管肺发育不良(BPD)差异有统计学意义(P <0. 05)。2组患儿坏死性小肠结肠炎(NEC)、早产儿视网膜病(ROP)、脑室旁白质软化(PVL)、出生体质量、能否遵医嘱出院回家方面比较,差异无统计学意义(P> 0. 05)。结论极低、超低出生体质量儿中,母亲妊娠高血压与其婴儿支气管肺发育不良、颅内出血、败血症发生率有关。
Objective To explore the relationship between pregnancy-induced hypertension syndrome （PIH） and complications in infants with very low and extremely low birth weight. Methods A total of 336 infants with very low and extremely low birth weight were selected and divided into PIH group and non-PIH group according to the presence or absence of PIH in mothers. The general condition and incidence of major complications were compared between the two groups. Results Finally 291 cases were selected and divided into PIH group （ n =84） and non-PIH group （ n =207）. There were significant differences in gestational age, cesarean section, maternal age, Apgar score at 5 min and ratio of infants less than gestational age between the two groups （ P 〈0.05）. There were significant differences in sepsis, intracranial hemorrhage and bronchopulmonary dysplasia （BPD） between the two groups （ P 〈0.05）. There were no significant differences in necrotizing enterocolitis （NEC）, retinopathy of premature infants （ROP）, paraventricular leukomalacia （PVL）, birth weight, and whether or not to follow the doctor′s instructions to leave the hospital between the two groups （ P 〉0.05）. Conclusions In infants with very low and extremely low birth weight, maternal hypertension in mothers is related to the incidence rates of bronchopulmonary dysplasia, intracranial hemorrhage and septicemia in infants.
作者
沈莉荣
杨祖铭
杨晓路
朱梅英
蔡燕
王三南
SHEN Lirong;YANG Zuming;YANG Xiaolu;ZHU Meiying;CAI Yan;WANG Sannan(Department of Neonatology,Suzhou Municipal Hospital,Suzhou Hospital Affiliatedto Nanjing Medical University,Suzhou,Jiangsu,215002)
出处
《实用临床医药杂志》
CAS
2018年第22期65-67,共3页
Journal of Clinical Medicine in Practice
关键词
妊娠高血压综台征
新生儿
体质量
坏死性小肠结肠炎
并发症
pregnancy-induced hypertension syndrome
neonates
body weight
necrotizing enterocolitis
complications
