摘要
为探讨全身麻醉联合硬膜外麻醉在直肠癌根治手术中的临床效果,将2015年9月至2017年8月我院收治的140例直肠癌患者,随机分为对照组和观察组,每组各70例。在直肠癌根治手术中,对照组给予全身麻醉,观察组给予全身麻醉联合硬膜外麻醉。比较2组患者每个时期(麻醉时、插管时、拔管时、拔管后20 min)的血压、心率、不良反应率,以及治疗总有效率。结果显示,观察组患者在麻醉、插管、拔管时和拔管后20 min的血压分别为(84.2±2.9) mmHg、(82.0±3.9) mmHg、(81.0±3.7) mmHg、(85.2±4.0) mmHg,心率分别为(80.9±8.9)次/分、(77.9±9.8)次/分、(79.1±10.7)次/分、(82.1±11.9)次/分,显著下降且之后均趋于平稳,而对照组血压及心率上升且不稳定,2组数据对比差异具有统计学意义(P <0.05)。对照组患者不良反应发生率为10.00%,明显高于观察组的2.86%,P<0.05。观察组患者治疗总有效率为97.14%(68/70),对照组为85.71%(60/70),观察组显著优于对照组,差异具有统计学意义(P <0.05)。结果表明,直肠癌根治手术中全身麻醉复合硬膜外麻醉的临床效果显著,较单纯应用全身麻醉,患者生命体征更平稳,对患者的免疫功能影响更小,不良反应发生率低,安全性高,具有临床应用及推广价值。
To investigate the clinical efficacy of general and epidural compound anesthesia （GECA） in rec- tal carcinoma radical surgery,140 cases admitted in author＇s hospital（2015-09--2017-08） were randomly di- vided into control group（70 cases,under general anesthesia） and observation group （70 cases, under above compound anesthesia）, then both group＇s blood pressure（BP）, heart rate（HR）, untoward reaction incidence at following time points（anesthesia,intubation,extubation and 20 rain after extubation）, and total effective rate were compared.As results,in above all indexes observation group was all superior to control one[at 4 time points,BP.（84.2±2.9）mmHg,（82.0±3.9） mmHg,（81.0±3.7） mmHg,（85.2±4.0） mmHg;HR. （80.9±8.9） times/min, （77.9 ± 9.8） times/rain, （79.1 ± 10.7） times/rain, （82.1 ± 11.9） times/min; unto- ward reaction incidence. 2.86 % vs 10.00%;total effective rate： 97.14% （68/70） vs 85.7（60/70）] ,there was significantly statistical difference between the two groups,all, P 〈0.05.as for BP,obsevation group be- come stable following signficantly declined,but in control group BP and HR uplifted and unstable.Results show that above compound anesthesia has significant clinical efficacy, and less influence on patients＇ immu- no-function,lower untoward reaction incidence,higher safety and more stable patients＇ vital signs than a- lone general anesthesia.It has clinical application and popularization value.
作者
滕晓君
TENG Xiao-jun(Anesthesia Dept.,the People＇s Hospital of Jian＇an District,Xuchang,Henan 461000)
出处
《中国肛肠病杂志》
2018年第9期15-17,共3页
Chinese Journal of Coloproctology
关键词
直肠癌根治术
全身麻醉
硬膜外麻醉
临床效果
Rectal carcinoma radical surgery
General anesthesia
Epidural anesthesia
Clincial efficacy
