摘要
目的探讨血浆置换在抢救妊娠导致血栓性血小板减少性紫癜的临床治疗效果。方法使用血浆单采机于患者入院后单采血浆,1次/d,连续3 d,同时补充等量新鲜冰冻血浆和（或）血浆代用品。置换前24 h,置换1次、2次、3次及治疗后24 h、48 h血小板计数、红细胞计数、血红蛋白含量和患者出凝血时间、纤维蛋白原含量。结果完成治疗后,同治疗前进行比较,血小板计数由6×109/L升至70×109/L,红细胞计数由2. 03×1012/L升至2. 83×1012/L,血红蛋白由64g/L升至91g/L,出凝血时间均在正常范围内。结论血浆置换能迅速改善妊娠导致的血栓性血小板减少性紫癜微血管病性溶血性病变,减少血小板聚集性消耗,安全有效。
Objective To investigate the clinical effect of plasma exchange（ PE） in thrombotic thrombocytopenic purpura pregnancy.Methods After the case was diagnosed,PE was performed daily,for a total of 3 times. The datas about blood routine examination and hemagglutination in different points were analyzed. Results Clinical symptoms were significantly improved in this patient. The count of Plt were increased from 6×109/L to 70×109/L,as the hemoglobin was increased from 64 g/L to 91 g/L. The change of hemagglutination was acceptable. Conclusion This case illustrates that plasma exchange wasefficacy and safetyinthrombotic thrombocytopenic purpura pregnancy. TPE has significantly decreased assemble of PLT and improved patients＇ microangiopathic hemolytic anemia caused by pregnancy.
作者
夏爱军
党娥
陈晓鹏
尹文
XIA Aijun;DANG E;CHEN Xiaopeng;YIN Wen(Department of TransfusionMedicine,Xijing Hospital,The Air Force Military Medical U-niversity,Xian 710032,China.)
出处
《中国输血杂志》
CAS
2018年第9期1040-1042,共3页
Chinese Journal of Blood Transfusion
关键词
血浆置换
血栓性血小板减少性紫癜
妊娠
therapeutic plasma exchange （TPE）
thrombotic thrombocytopenic purpura （ TTP）
pregnancy
