摘要
目的探讨动态检测血清降钙素原(procalcitonin,PCT)在<36周胎膜早破孕妇预测亚临床绒毛膜羊膜炎的价值。方法选取2015年7月至2017年5月在上海市嘉定区妇幼保健院住院治疗的<36周未足月胎膜早破孕妇120例,根据孕妇分娩日血清PCT的水平分为3组:正常组(PCT <0. 1 ng/m L) 49例、动态变化组(PCT 0. 1～0. 5 ng/m L) 43例及异常组(PCT> 0. 5 ng/m L) 28例。检测3组孕妇入院时、入院第3 d及分娩时的PCT水平,并比较各组孕妇胎膜破裂至分娩时间、分娩方式、新生儿出生体重、出生1 min Apgar评分及亚临床绒毛膜羊膜炎的发生率。结果与正常组及动态变化组相比,异常组孕妇入院时、入院第3 d及分娩时的PCT水平均显著升高;胎膜破裂至分娩时间缩短;剖宫产率提高;新生儿出生体重及出生1 min Apgar评分均显著降低,差异均有统计学意义(P <0. 05)。结论动态检测血清PCT对<36周胎膜早破孕妇亚临床绒毛膜羊膜炎的发生具有一定的预测价值。
Objective To investigate the value of dynamic detection of the level of procalcitonin（ PCT） for prediction of subclinical chorioamnionitis in pregnant women less than 36 gestational weeks with premature rupture of membranes. Methods 120 pregnant women with preterm premature rupture of membranes less than 36 gestational weeks were collected from July 2015 to May2017 in Jiading District Maternal and Child Health Hospital of Shanghai,according to the level of PCT in dilivery day divided into three groups： normal group（ serum PCT level less than 0. 1 ng/m L,49 cases）,dynamic change group（ serum PCT level between 0. 1～ 0. 5 ng/m L,43 cases） and abnormal group（ serum PCT level more than 0. 5 ng/m L,28 cases）. Tested the level of PCT at admission,3 rd day of admission and childbirth,and compared the time from membranes rupture to delivery,delivery mode,the neonatal birth weight,1 min Apgar score and the incidence of the subclinical chroioamnionitis. Results Compared with the normal group and dynamic change group,the level of PCT at admission,3 rd day of admission and childbirth of the abnormal group significantly increased,the time from membranes rupture to delivery significantly shorten,but the rate of cesarean delivery significantly increased,the neonatal birth weight and 1 min Apgar score significantly decreased. The differences were statistically significant（ P〈0. 05）. Conclusion Dynamic detection of the level of PCT has a certain value for predicting the subclinical chorioamnionitis in pregnant women less than 36 gestational weeks with premature rupture of membranes.
作者
高永妹
陆勤
邓娟
GAO Yong-mei;LU Qin;DENG Juan(Department of Obstetrics,Jiading District Maternal and Child Health Hospital of Shanghai,Shanghai 201821,P.R.China)
出处
《中国计划生育和妇产科》
2018年第11期55-58,F0003,共5页
Chinese Journal of Family Planning & Gynecotokology
基金
2014年上海市卫生和计划生育委员会科研课题(项目编号:201440001)
关键词
降钙素原
未足月胎膜早破
孕妇
亚临床绒毛膜羊膜炎
procalcitonin
preterm premature rupture of membranes
pregnant woman
subclinical chorioamnionitis
