摘要
目的探讨颅内压监测指导下治疗方案对重型颅脑损伤的治疗价值。方法回顾性分析2015年3月至2018年3月收治的200例重型颅脑损伤的临床资料。根据治疗方案分为观察组和对照组,各100例。对照组采用常规治疗,观察组采用颅内压监测指导下治疗方案。结果观察组痊愈35例,显效40例,有效15例,无效10例;对照组痊愈16例,显效36例,有效20例,无效28例。观察组治疗有效率(90.0%)明显高于对照组(72.0%;P<0.05)。治疗7 d,观察组甘露醇应用量、甘露醇应用时间、NICU住院时间较对照组均明显减少(P<0.05),GCS评分明显增高(P<0.05)。观察组发生肺部感染21例(21.0%)、脑疝5例(5.0%)、颅内感染6例(6.0%);对照组肺部感染46例(46.0%)、脑疝24例(24.0%)、颅内感染19例(19.0%)。观察组肺部感染、脑疝、颅内感染等发生发生率明显低于对照组(P<0.05)。结论对重型颅脑损伤,颅内压监测指导下治疗方案有助于将颅内压控制于理想水平,从而改善临床疗效。
Objective To study the value of intracranial pressure （ICP） monitoring to the treatment of severe craniocerebral trauma
（sCCT）. Methods Two hundred patents with sCCT were divided into two groups of 100 patients each, i.e. control group in which the
patients were given conventional treatment, and the observed group in which the patients were given treatment under the guidance of ICP
monitoring. The clinical effects, the rate of complications occurrence and so on were compared between the two groups. Results The total
effective rate was significantly higher in the observed group than that in the control group （P〈0.05）. The amount of administered mannitol
was significantly less and hospital stay in neurosurgical intensive care unit were significantly shorter in the observed group than those in
the control group （P〈0.05）. The rates of the lung infection, brain herniation and intracranial infection were significantly lower in the
observed group than those in the control group （P〈0.05）. Conclusion The ICP monitoring is of great value to the treatment of patients
with sCCT and it is worthy of clinical popularization.
作者
吴勇
申松波
胡胜
吕华荣
刘强
杨浩
WU Yong;SHEN Song-bo;HU Sheng;Lü Hua-rong;LIU Qiang;YANG Hao(Department of Neurosurgery,Huangshi CentralHospital,Affiliated Hospital of Hubei Polytechnic University,Edong Healthcare Group,Huangshi 435000,China;Department ofClinical Laboratory,Huangshi Central Hospital,Affiliated Hospital of Hubei Polytechnic University,Edong Healthcare Group,Huangshi435000,China)
出处
《中国临床神经外科杂志》
2018年第11期717-719,共3页
Chinese Journal of Clinical Neurosurgery
基金
湖北省自然科学基金(2015CFB627)
关键词
重型颅脑损伤
颅内压监测
治疗
疗效
Severe craniocerebral trauma
Intracranial pressure monitoring
Treatment
Value
