摘要
目的探讨彩色多普勒超声诊断甲状腺髓样癌(MTC)的临床价值。方法回顾性分析经手术治疗的48例MTC患者的临床资料,对MTC患者行彩色多普勒超声探查及组织病理学检查,以组织病理学检查为金标准,比较彩色多普勒超声与组织病理学检查对MTC的诊断结果。结果彩色多普勒超声检查与组织病理学检查结果比较,差异无统计学意义[χ~2(校正)=0.1667,P=0.683]。彩色多普勒声诊断MTC的灵敏度为95.24%,特异度为60.00%,阳性预测值为90.91%,阴性预测值75.00%。多数MTC病灶边缘清晰,呈圆形或椭圆形,回声为实性低回声或极低回声,其内多钙化,易转移。结论彩色多普勒超声诊断MTC,与组织病理学诊断结果的吻合度较高,对MTC具有诊断价值,值得临床应用。
Objective To evaluate the clinical value of color Doppler ultrasound in the diagnosis of medullary thyroid carcinoma （MTC）.Method A retrospective analysis was perform for 48 patients with MTC who had surgical treatment, color Doppler ultrasound and histopathological examination were administered for these patients, with histopathological results as the gold standard, to compare the results of the two tests. Result There was no significant difference between the findings of color Doppler ultrasound and histopathological examination （adjusted χ2=0.1667, P=0.683）. The sensitivity, specificity, positive predictive value, and negative predictive value of color Doppler ultrasound were 95.24%, 60.00%, 90.91%, and 75.00%, respectively. Most MTC lesions were well defined as round or oval mass, with low solid echo or extremely low echo, remarkable calcification, and were highly metastatic. Conclusion The color Doppler ultrasound exhibits a remarkably high consistency in regard of MTC diagnosis compared with histopathological examinations, indicating great diagnostic value for MTC and is clinically applicable.
作者
高梅华
杨莲
张卫卫
GAO Meihua;YANG Lian;ZHANG Weiwei(Department of Ultrasound Imaging;Department of Surgery,Honghu People＇s Hospital,Honghu 433200,Hubei,China)
出处
《癌症进展》
2018年第12期1481-1483,共3页
Oncology Progress
关键词
彩色多普勒超声
甲状腺髓样癌
诊断
临床价值
color Doppler ultrasound
medullary thyroid carcinoma
diagnosis
clinical value
