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布地奈德联合孟鲁斯特治疗小儿哮喘临床疗效及其对患儿肺功能影响的研究 被引量:10

Clinical Effect of Budesonide Combined with Montelukast in Treating Infantile Asthma and its Effect on Pulmonary Function
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摘要 目的:分析布地奈德联合孟鲁斯特治疗小儿哮喘临床疗效及其对患儿肺功能的影响。方法:选择我科2017年1月~2017年12月收治的76例哮喘患儿作为研究对象,将这76例患儿随机分为实验组(38例)和常规组(38例),常规组仅采用布地奈德进行治疗,实验组采用布地奈德联合孟鲁斯特进行治疗,对比两组患儿的治疗效果、肺功能指标。结果:实验组患者的治疗总有效率(94.74%)显著高于常规组患者的治疗总有效率(73.68%),差异有统计学意义(P<0.05);实验组患者的多项肺功能参数相对于常规组而言均有明显的优势,两组患者肺功能差异显著,差异有统计学意义(P<0.05)。结论:布地奈德联合孟鲁斯特治疗小儿哮喘临床疗效显著,能够有效的改善临床症状,同时有效改善患儿肺部功能,从根本上减轻临床症状,提高生存质量,值得在小儿哮喘中推广。 Objective: To analyze the clinical efficacy of budesonide combined with montelukast in trea ting infantile asthma and its effect on pulmonary function. Methods: 76 children with asthma in our depart ment from January 2017 to December 2017 were selected, and the 76 cases were randomly assigned to the ex perimental group (38 cases) and the routine group (38 cases). The routine group was treated with budes onide, while the experimental group was treated with budesonide combined with montelukast. The therapeu tic effects and pulmonary function indexes of the two groups were compared. Results: The total effective rate of treatment in the experimental group (94. 74%) was significantly higher than that of the routine group (73.68%) (P〈0. 05). The pulmonary function parameters in the experimental group were obviously better compared with those of the routine group (P〈0.05). Conclusion: Budesonide combined with montelukast has a significant clinical effect in the treatment of childhood asthma. It can effectively improve the clinical function effectively, reduce the children's asthma. clinical symptoms and improve the quality of life. It is worth promoting in children's asthma.
作者 倪田楷 李昌崇 吴超雄 Ni Tiankai(Wenzhou Medical University,Wenzhou 32500)
出处 《数理医药学杂志》 2018年第12期1835-1837,共3页 Journal of Mathematical Medicine
关键词 布地奈德 孟鲁斯特 小儿哮喘 疗效 budesonide montelukast infantile asthma clinical nursing
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