摘要
目的观察肺癌患者中心静脉导管(peripherally inserted central catheter,PICC)相关性血流感染目标性监测结果,探讨银离子敷料对其预防效果,为临床提供有效预防方法。方法选择2015年6月-2017年6月医院接诊398例肺癌经PICC用药患者,其中2015年6月-2016年6月的200例患者作为对照组,2016年7月-2017年6月的198例患者作为试验组患者。PICC术后对照组患者给予传统常规敷料,试验组患者给予银离子敷料进行敷贴。回顾性分析两组患者一般临床资料、PICC术后感染情况、疼痛情况、伤口愈合情况和不良反应发生情况。结果试验组患者的感染发生率为2.52%(5/198),低于对照组患者11.00%(22/200)(P=0.001);试验组患者的千日导管血流感染率为0.34‰(5/14 738),低于对照组患者1.50‰(22/14 657)(P=0.001);试验组患者疼痛程度较对照组患者轻(P<0.001);试验组患者术后6、9、15d伤口愈合情况均优于对照组患者(P<0.001)。结论对肺癌患者PICC相关性血流感染目标性监测发现,银离子敷料的运用可有效降低感染的发生率,且能较好地改善术后疼痛情况和促进伤口愈合,可有效预防肺癌患者PICC相关性血流感染的发生。
OBJECTIVE To observe the result of targeted monitoring of peripherally inserted central catheter（PICC）-related bloodstream infection in lung cancer patients and explore the effect of silver ion dressing on prevention of the infection so as to put forward effective prevention measures.METHODS A total of 398 lung cancer patients who were treated with PICC drug administration in the hospital from Jun 2015 to Jun 2017 wee enrolled in the study,200 patients who were treated from Jun 2015 to Jun 2016 were assigned as the control group,and 198 patients who were treated from Jul 2016 to Jun 2017 were set as the experimental group.The control group was given conventional dressings,while the experimental group was given application of silver ion dressing.The baseline clinical data,incidence of postoperative PICC-related infection,pain degree,wound healing and incidence of adverse reactions were retrospectively analyzed.RESULTS The incidence rate of infection of the experimental group was 2.52%（5/198）,significantly lower than 11.00%（22/200）of the control group（P=0.001）.The incidence of1000-day catheter-related bloodstream infection of the experimental group was 0.34‰（5/14738）,significantly lower than 1.50‰（22/14657）of the control group（P=0.001）.The pain degree of the experimental group was significantly less than that of the control group（P〈0.001）.The wound healing of the experimental group was significantly better than that of the control group after the surgery for 6,9 and 15 days（P〈0.001）.CONCLUSIONS The targeted monitoring of the lung cancer patients with PICC-related bloodstream infection shows that the silver ion dressing may effectively reduce the incidence of infection,alleviate the postoperative pain and promote the wound healing so as to effectively prevent the PICC-related bloodstream infection in the lung cancer patients.
作者
鲁燕
张华
张幸华
董霞
刘晓辉
LU Yan;ZHANG Hua;ZHANG Xing-hua;DONG Xia;LIU Xiao-hui(Henan Traditional Chinese Medicine Hospital,The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine）,Zhengzhou,Henan 450002,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2018年第21期3245-3248,共4页
Chinese Journal of Nosocomiology
基金
2016年度河南省中医药科学研究基金资助项目(2016ZY2060)
关键词
肺癌
PICC
银离子敷料
血流感染
Lung cancer
Silver ion dressing
Bloodstream infection
