摘要
目的探究婴幼儿轮状病毒肠炎使用锌制剂治疗效果以及后续3个月再复发腹泻预防作用。方法回顾性分析本院2015年6月～2016年10月收入142例轮转病毒性肠炎患儿作为本次研究对象,按照治疗方式不同分为观察组47例,对照组95例,对照组予以常规治疗,观察组在常规治疗上予以锌制剂治疗,比较两组治疗效果、治疗前后阳性症状持续时间、3个月后继发腹泻情况。结果两组临床治疗有效率比较中观察组治疗总有效率高于对照组,差异有统计学意义(P <0.05),两组治疗前高热、呕吐、腹泻时间比较差异无统计学意义(P> 0.05),两组治疗后高热、呕吐、腹泻时间,差异有统计学意义(P <0.05),观察组1个月后腹泻复发率低于对照组,2个月腹泻复发率低于对照组,观察组3个月后腹泻复发率低于对照组,差异有统计学意义(P <0.05)。结论婴幼儿轮状病毒性肠炎予以常规治疗联合锌制剂,可以提高临床治疗效果,减少后期疾病复发率。
Objective To explore the therapeutic effect of zinc preparation on infantile rotavirus enteritis and the preventive effect of recurrent diarrhea in the following three months. Methods Data retrospective analysis of 142eases of children with recurrent viral enteritis from June 2015 to October 2016 were divided into observation group （47 eases） and control group （95 eases）. The control group was treated with routine treatment,while the observation group was treated with zinc preparations in routine treatment.The therapeutic effeet,pre-treatment and post-treatment of the two groups were compared.Duration of positive symptoms and secondary diarrhea after 3 months. Results The total effective rate of the two groups was higher than that of the control group.The difference between the two groups was significant （P 〈 0.05）.There was no significant difference in the time of high fever,vomiting and diarrhea before treatment between the two groups （P 〉 0.05）.There was significant difference in the time of high fever,vomiting and diarrhea after treatment between the two groups （P 〈 0.05）.The recurrence rate of diarrhea in the observation group lower than that in the control group after 1 month.The recurrence rate of diarrhea in 2 months lower than that in the control group.The recurrence rate of diarrhea in the observation group was after 3 months,which was lower than that in the control group.The difference between the two groups was significant （P 〈 0.05）. Conclusion Routine treatment of infantile rotavirus enteritis combined with zine preparation can improve the clinical therapeutic effect and reduce the recurrence rate of late disease.
作者
叶秋娟
廖翠芳
YE Qiujuan;LIAO Cuifang(Department of Pediatric Clinic,the Maternal and Child Health Hospital,Guangdong Province,Heyuan 517000,China)
出处
《中国医药科学》
2018年第20期71-73,83,共4页
China Medicine And Pharmacy
关键词
锌制剂
轮状病毒性肠炎
腹泻
治疗效果
Zinc preparation
Rotavirus enteritis
Diarrhea
Treatment effect
