摘要
目的:评价补肾活血通络方联合针刺治疗神经根型颈椎病的临床疗效。方法:选择神经根型颈椎病患者110例,根据Excel随机表格法将患者分为试验组和对照组,每组55例。对照组采用颈舒颗粒联合针灸治疗,试验组采用补肾活血通络方联合针刺治疗。两组均治疗14d,比较两组治疗疗效,治疗前后CASCS和VAS评分,中医症候积分和NDI(颈椎功能障碍指数),血清炎性因子IL-1β,TNF-α及IL-6水平。结果:试验组治疗总有效率为92.73%,高于对照组治疗总有效率78.18%,差异有统计学意义(P<0.05);试验组治疗后CASCS评分高于对照组,VAS评分低于对照组,差异有统计学意义(P<0.05);试验组治疗后中医症候积分和颈椎功能障碍指数低于对照组,差异有统计学意义(P<0.05);试验组治疗后血清炎性因子IL-1β,TNF-α及IL-6水平低于对照组,差异有统计学意义(P<0.05)。结论:补肾活血通络方联合针刺可以改善神经根型颈椎病的临床症状,提高日常活动能力,减轻疼痛,下调炎性细胞因子水平,提高治疗效果,值得临床推广应用。
Objective：To evaluate the effect of Bushen Huoxue Tongluo recipe combined with acupuncture on serum inflam- matory factors IL-1, TNF-α and IL-6 in patients with cervical spondylotic radieular disease. Methods：110 patients with cervical spondylotic radicular disease were selected and divided into the experimental group and the control group accord- ing to the Excel random table method, 55 cases in each group. The control group was treated with Jinshu granule com- bined with acupuncture. The experimental group was treated with Bushen Huoxue Tongluo Decoction plus acupuncture. The two groups were treated with 14d. The therapeutic effect of the two groups, the scores of CASCS and VAS before and after the treatment, the TCM syndrome score and the NDI cervical dysfunction index, the serum inflammatory factor IL-1β TNF-α and IL-6 levels were compared. Results：The results showed that the total effective rate of treatment in the experimental group was 92.73% higher than that of the control group （P〈0.05）. The CASCS score of the experimental group was higher than that of the control group, and the VAS score was lower than that of the control group （P〈0.05）. The TCM Syndrome score and the NDI cervical dysfunction index were lower than those of the control group after treat- ment （P〈0.05）. After treatment, serum inflammatory factors IL-1β, TNF-α and IL-6 levels in experimental group were lower than those in control group （P〈0.05）. Conelusion：The combination of Bushen Huoxue Tongluo recipe combined with acupuncture can effectively improve the clinical symptoms of nerve root type cervical spondylosis, improve the ability of daily activity, reduce pain, reduce the level of inflammatory cytokines and improve the therapeutic effect. It is worthy of clinical application.
作者
刘波
苏小强
王向阳
LIU Bo;SU Xiaoqiang;WANG Xiangyang(Department of Orthopedics,Xi＇an Hospital of Traditional Chinese Medicine,Xi＇an 710021,China.)
出处
《中国中医骨伤科杂志》
CAS
2018年第11期21-24,共4页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
西安市科技计划项目(2016050SF/YX06)
关键词
补肾活血通络方
针刺
神经根型颈椎病
影响
Bushen Huoxue Tongluo recipe
acupuncture
cervical spondylotic radicular disease
influence
