摘要
目的:观察星状神经节阻滞(SGB)联合甲钴胺、维生素B_(12)对神经性耳鸣的疗效。方法:神经性耳鸣患者100例,依据随机分配原则分为常规组和SGB组,每组50例。常规组给予0. 5 mg甲钴胺和500 mg维生素B_(12)注射治疗,1次/d,共30 d,SGB组在此基础上给予SGB治疗,1次/d,共12 d。结果:治疗后2组基底动脉血流收缩末期峰值(Vs)、舒张末期峰值(Vd)水平明显高于治疗前,且SGB组明显优于常规组(均P <0. 05); SGB组治疗有效率明显高于常规组,SGB组6个月复发率明显低于常规组(均P <0. 05),SGB组治疗不良事件率高于常规组,但差异无统计学意义(P> 0. 05)。结论:SGB联合甲钴胺、维生素B_(12)可有效改善神经性耳鸣患者内耳血液微循环,减轻神经性耳鸣,提高患者的近远期疗效。
objective： To discuss the curative effect of stellate ganglion block（ SGB） combined with methylamine treatment for neuro tinnitus. Methods： According to the random distribution,100 patients with neuro tinnitus were divided into control group and SGB group,50 cases in each group. The control group and SGB group were given 0. 5 mg methylamine and500 mg vitamin B12 injection treatment,once every day for a total of 30 days. Additionally,the SGB group received SGB treatment,5 times every day,a total of 30 days. Results： The basilar artery blood flow（ Vs） and late diastolic peak systolic peak（ Vd） levels after treatment in control group and SGB group were significantly higher than those before treatment,and the effect in SGB group was significantly better than in control group with the difference being statistically significant（ P 〈0. 05）. The therapeutic response rate in SGB group was significantly higher and the 6-month recurrent rate in SGB group was significantly lower than in the control group（ both P 〈0. 05）. The incidence of adverse events in SGB group was higher than in control group,but there was no statistically significant difference（ P 〉0. 05）. Conclusions： SGB combined with methylamine treatment can effectively improve the inner ear blood microcirculation of patients with neuro tinnitus,and improve the patients＇ near and forward future curative effect.
作者
袁景和
YUAN Jing-he(Yan＇an University Affiliated Hospital,Yan＇an 716000,China)
出处
《内科急危重症杂志》
2018年第5期403-405,共3页
Journal of Critical Care In Internal Medicine
