摘要
目的:探讨同步水降温法对卵巢腹腔镜手术中卵巢储备功能的影响。方法:选取2016-08-01～2017-08-01我院收治的卵巢囊肿患者120例,按照随机数字表法分为对照组和研究组,每组60例。对照组在腹腔镜下卵巢囊肿剥除后给予常规止血,即直接缝合创口,手术结束时再予创面冲洗;研究组使用自主改良的具有电凝与冲洗双重功能电凝器械,在腹腔镜卵巢囊肿剥除后电凝止血,同时给予25℃常温生理盐水(研究组)冲洗卵巢创面。观察对比两组患者的卵巢囊肿术前情况、卵巢储备功能、手术前后激素水平。结果:两组术前年龄、囊肿直径、囊肿性质(巧克力囊肿、畸胎瘤和上皮性囊肿)、促黄体生成素(luteinizing hormone,LH)、卵泡刺激素(follicle-stimulating hormone,FSH)、雌二醇(estradiol,E2)、血清抑制素B(inhibin B,INHB)、卵巢大小、窦卵泡个数(antral follicle counting,AFC)和卵巢峰值血流速度(peak systolic velocity,PSV)比较,无明显差异(P>0.05)。治疗后研究组的FSH、LH低于对照组,AFC、血清INHB和E2水平显著高于对照组(P<0.05)。常温研究组术后的卵巢大小、PSV及变异数分析F值都明显高于对照组(P<0.05)。结论:同步水降温法在腹腔镜下卵巢囊肿剔除术中具有较好的应用效果,有利于维持正常卵巢储备功能,可在临床大力推广。
Objective：To study the protection effect of synchronous water-cooling methods on ovarian reserve function during the laparoscopic surgery.Methods：A total of 120 patients with ovarian cyst treated from August 2016 to August 2017 in our hospital were selected.The subjects were randomly divided into control group and study group,60 patients in each group.After the laparoscopic resection of ovarian cyst and electric coagulation hemostasis,the control group received the wound-flushing method,and the study group received the autonomously modified instrument provided with electrocoagulation and flushing function in flushing the wound with 25℃room temperature of normal saline after the electric coagulation hemostasis.The perioperative conditions,ovarian reserve function and hormone levels among three groups were compared.Results：The patient′s age and the size of cyst between the study group and control group showed no statistical difference（P〈0.05）.The cyst property（chocolate cyst,teratoma,epithelial cyst）,sex hormone levels including luteinizing hormone（LH）,folliclestimulation hormone（FSH）and estradiol（E2）as well as ovarian volume,antral follicle count（AFC）,Inhibin B（INHB）and peak systolic velocity（PSV）between the study group and control group showed no statistical differences before treatment（P〈0.05）.After treatment,the values of FSH and LH in the study group were lower than those of control group,and the values of AFC,INHB and E2 were higher than those of control group,there were statistical differences between study group and control group（P〈0.05）.The ovarian volume,PSV and analysis of variance Fvalues in the study group were higher than those in control group（P〈0.05）.Conclusion：Clinical efficacy of the synchronous water-cooling methods is better than electrocoagulation,can keep the normal ovarian reserve function.It shall be widely applied in clinical practice.
作者
范文娟
宣毅飞
王竹君
FAN Wenjuan;XUAN Yifei;WANG Zhujun(Department of Obstetrics ＆ Gynecology,the NO.184 Hospital of PLA,Yingtan 335000,China)
出处
《西北国防医学杂志》
CAS
2018年第10期658-662,共5页
Medical Journal of National Defending Forces in Northwest China
基金
南京军区医药卫生科研基金资助项目(15MS091)
关键词
卵巢腹腔镜
同步水降温法
卵巢储备功能
电凝术
laparoscopic surgery
synchronous water-cooling methods
ovarian reservefunction
electrocoagulation
