摘要
为探讨抗子宫内膜抗体在子宫内膜异位症诊断和治疗中的作用以及活血化瘀消中药对其的影响 ,将经病检、腹腔镜或临床确诊为子宫内膜异位症 (EMT)的 97例患者随机分为治疗组 65例 ,对照组 32例 ,分别用理气活血、化瘀消的莪棱胶囊和西药丹那唑治疗两个疗程 ,观察运用ELISA法检测血清抗子宫内膜抗体 (EmAb)的阳性率和治疗后的阴转率。结果 :①EmAb的阳性率、阴转率都与病情程度相关。轻、中度者阳性率较高 ,分别为 66.67%和 76.19% ,重度者仅为 5 7.45 % ;轻度者阴转率较高为 85 .71% ,中、重度者分别为 41.67%和 5 0 .0 % ;②治疗组的患者阴转率为 5 1.85 % ,对照组为 5 6.2 5 % ,两组患者阴转率相当 (P >0 .0 5 )。提示 :EmAb的阳性率不随病情严重程度而上升 ,它对病情较轻者有更好的辅助诊断价值 ,且治疗后易阴转 ,推测可能与重度者抗体移至盆、腹腔致检出率低 ,轻度者血清中免疫反应易受到抑制有关 ;莪棱胶囊具有较强的免疫调节作用 。
To assess the significance of endometrial antibody(EmAb)for the diagnosis and treatment of endometriosis(EMT),and the influence of Eleng Capsule(EC)on EMT,97 cases of EMT confirmed by pathological examination and laparoscopy were randomly allocated to 2 groups:EC group (65 cases,treated by EC 6 tid for 6 months)and control group (32 cases,treated by danazol 0.2 bid for 6 months).Serum EmAb content was detected by enzyme linked immunosorbent assay method.The severity of the disease was classified into three grades(mild,moderate and severe).The results showed that the positive rate of EmAb in the mild,moderate and severe cases was 66.67% , 76.19% and 57.45%, and the rate of EmAb turning to negative was 85.71% , 41.67% and 50.00% respectively.The rate of EmAb turning to negative was 51.85% and 56.25% in EC group and control group respectively (P> 0.05 ).It is suggested that the positive rate of EmAb does not elevate with the severity of EMT.EmAb is more significant for the complementary diagnosis of mild cases and can turn negative easily after treatment.It is probably related to the transmission of EmAb to pelvic cavity and abdominal cavity in severe cases and the serum immune response being easily inhibited in mild cases.EC exerts a strong immunoregulatory effect and inhibit the level of serum EmAb.
出处
《广州中医药大学学报》
CAS
1999年第3期76-78,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
子宫内膜异位症
理气
活血祛瘀
莪棱胶囊
中医治疗
抗子宫内膜抗体
ENDOMETRIOSIS/immunology
ENDOMETRIOSIS/TCD therapy
@ENDOMETRIUM ANTIBODY/immunology
REGULATING QI
BLOOD ACT STASIS REMOV
@ELENG CAPSULE/ther.use
