摘要
以紫苏籽油为原料,利用碱催化条件下的酯交换反应,得到α-亚麻酸乙酯粗品,再用尿素包合法对α-亚麻酸乙酯粗品进行分离纯化,得到高纯度的α-亚麻酸乙酯,并对高纯度的α-亚麻酸乙酯建立初步质量评价体系。整个实验过程设计紧凑,安排合理,将理论知识灵活应用到实验课程中,涉及知识面广,实践性和应用性强,可作为综合性实验,大大提高学生对实验课程的兴趣。
High purified α-ethyl linolenate was prepared through interesterification in basic condition by using perilla oil as material,and purified by urea adduction. The primary evaluation system of high purified α-ethyl linolenate was established,including the determination of acid value,iodine value,peroxide value,etc. The whole experimentation was well-designed,involved wide knowledge,applied theoretical knowledge to experimental courses flexibly,so it had the practical and applied nature. The experimentation can be used as a teaching case of integrative experiment,to enhance students＇ interest in experimental curriculum.
作者
段建利
DUAN Jian-li(Provincial Demonstration Center of Experimental Pharmaceutical Teaching,School of Pharmaceutical Sciences,Wuhan University,Hubei Wuhan 430071,China)
出处
《广州化工》
CAS
2018年第22期105-107,共3页
GuangZhou Chemical Industry
基金
武汉大学教学研究项目(2017JG056)
武汉大学医学部教学研究项目(2018070)
关键词
Α-亚麻酸乙酯
尿素包合
酯交换
α-ethyl linolenate
urea adduction
interesterification
