摘要
目的:探讨反流症状指数评分表(RSI)对过敏合并咽喉反流(LPR)的诊断价值及最佳诊断阈值。方法:选取有呼吸道症状的成年过敏患者,经患者同意后每位患者均完成RSI量表,从中筛选出RSI>13分的患者共150例。采用咽喉食管24hpH值监测确诊为LPR患者(过敏组),选取相同例数不合并过敏因素的LPR患者作为对照组(非过敏组)。计算RSI>13分的过敏组患者确诊为LPR的比率。比较过敏组及非过敏组的RSI量表总分及每项评分。ROC曲线分析过敏患者诊断反流性咽喉炎高度可疑的RSI量表评分阈值。结果:过敏组RSI>13分的150例患者中,经过咽喉食管24hpH监测,仅有53例(35.33%)患者确诊为LPR。RSI评分量表的9项症状中,6项症状过敏组评分明显高于非过敏组(均P<0.05)。过敏组RSI评分总分平均为(23.57±3.17)分,非过敏组为(17.57±2.64)分,过敏组总分大于非过敏组(P<0.05)。根据过敏组RSI量表评分ROC曲线,95%可信区间曲线下面积为0.815,RSI评分对过敏患者诊断LPR具有一定的诊断准确性,诊断合并过敏的LPR患者RSI评分最佳临界值为18分,敏感度为94.3%,特异性为56.7%。结论:RSI量表可用于筛选过敏患者合并LPR,诊断评分阈值RSI>18分,具有一定的诊断准确性。
Objective：To explore the diagnostic value and optimal diagnostic threshold of reflux symptom index（RSI）in allergic patients with laryngopharyngeal reflux.Method：All the adult allergic patients with respiratory tract symptoms completed the RSI with the consent of the patients.A total of 150 patients with RSI〉13 were screened out.The LPR patients were confirmed by 24 h pH-metry of pharyngo-laryngoesophageal（allergic group）.The same number of non allergic laryngeal reflux patients were selected as control group（non allergic group）.The ratio of RSI〉13 to LPR was calculated.The total score of RSI and each score were compared between the allergic group and the non allergic group.ROC curve was used to analyze the highly suspicious RSI score thresholds for patients with reflux laryngitis.Result：Only 53（35.33%）of 150 patients with RSI〉13 were diagnosed as LPR after 24 hpH-metry test in allergic patients.Among the 9 symptoms of RSI,the scores of 6 symptoms in allergic group were significantly higher than those in non allergic group（P〈0.05）.The average RSI score of allergic group was 23.57±3.17.The average RSI score of non allergic group was 17.57±2.64.The total score of allergic group was higher than that of non allergic group（P〈0.05）.According to the RSI score ROC curve of allergic group,the area under 95%confidence interval curve was 0.815.RSI had certain diagnostic accuracy for allergic patients with LPR.The best critical value of RSI score for allergic patients with LPR was 18,the sensitivity was 94.3%,and the specificity was 56.7%.Conclusion：RSI can be used to screen allergic patients with LPR,diagnostic score threshold RSI〉18 points,has a certain diagnostic accuracy.
作者
齐智伟
张淑君
张宇丽
苏锐锋
黄跃燕
QI Zhiwei;ZHANG Shujun;ZHANG Yuli;SU Ruifeng;HUANG Yueyan(Department of Otolaryngology,the Affiliated Hospital of Chengde Medical University,Chengde,067000,China)
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2018年第22期1711-1713,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
