摘要
目的研究维持性血透患者股静脉留置临时中心静脉导管发生深静脉血栓(DVT)的原因。方法对2015年6月至2016年6月在我院接受维持性血液透析于股静脉留置临时中心静脉导管的138例患者的资料进行回顾,其中14例患者发生DVT,作为DVT组,其他124例作为非DVT组,分析DVT发生的危险因素。结果两组年龄、体质量、血小板计数、凝血酶原时间、活化部分凝血活酶时间、D二聚体、纤维蛋白原、置管前水肿、使用低相对分子质量肝素、病理类型为糖尿病肾病者之间存在显著性差异(P<0.05),而体温、血红蛋白、血细胞计数、血肌酐、尿素氮、总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白、白蛋白、服用前列腺素E1、服用阿司匹林和病理类型为慢性肾小球肾炎者之间差异不显著(P>0.05);多因素logistic回归分析结果显示,年龄、体质量和糖尿病肾病是股静脉留置临时中心静脉导管发生DVT的独立危险因素。结论高龄、低体质量和患糖尿病肾病是股静脉留置中心静脉导管患者发生DVT的独立危险因素。
Objective To investigate the causes of deep vein thrombosis（DVT） of femoral venous indwelling temporary central venous catheter in patients undergoing maintenance hemodialysis.Methods The data of 138 patients who received maintenance hemodialysis and emoral venous indwelling temporary central venous catheter in our hospital between June 2015 and June 2016 were reviewed.14 patients with DVT were included in DVT group and the other 124 cases were included in non-DVT group.The risk factors of DVT were analyzed.Results There were significant differences between the two groups in age,body weight,platelet count,prothrombin time,activated partial thromboplastin time,D-dimer,fibrinogen,edema before catheter,taking low molecular weight heparin and pathological type being diabetic nephropathy（P〈0.05） while there were no significant differences in temperature,hemoglobin,blood cell count,serum creatinine,urea nitrogen,total cholesterol,triglyceride,low-density lipoprotein,high-density lipoprotein,albumin,taking prostaglandin E1,taking aspirin and pathological type being chronic glomerulonephritis（P〈0.05）;Multivariate Logistic regression analysis showed that age,body massand diabetic nephropathy were independent risk factors of deep venous thrombosis of femoral venous indwelling temporary central venous catheter.Conclusion Age,low body weight and diabetic nephropathy are the independent risk factors of deep venous thrombosis of femoral venous indwelling temporary central venous catheter.
作者
薛箫
林朝霞
陈俊
吴萍
XUE Xiao;LIN Zhao-xia;CHEN Jun;WU Ping(Department of Nephrology,Central Hospital of Dazhou,Sichuan,Dazhou,635000,China)
出处
《血栓与止血学》
2018年第5期792-794,797,共4页
Chinese Journal of Thrombosis and Hemostasis
关键词
血液透析
中心静脉导管留置
股静脉
深静脉血栓形成
Hemodialysis
Central venous catheter indwelling
Femoral vein
Deep vein thrombosis
