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后腹腔镜根治性肾切除术与开放手术治疗T2期肾癌的临床疗效和安全性比较 被引量:18

Comparison of the clinical effectiveness and safety of retroperitoneal laparoscopic radical and open radical nephrectomy for stage T2 renal cancer
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摘要 目的 探讨后腹腔镜根治性肾切除术与开放手术治疗T2期肾癌的临床疗效和安全性.方法 回顾性分析2010年3月至2016年2月在本院收治的168例治疗T2期肾癌患者,分别采用了后腹腔镜根治性肾切除术与开放手术肾切除治疗.其中,后腹腔镜手术组(retroperitoneal laparoscopic radical nephrectomy,RLRN)77例,开放手术组(open radical nephrectomies of renal carcinoma,ORNRC)91例.两组患者均随访6个月,比较两组患者术中出血量、手术时间、术后进食时间以及住院时间.密切观察两组患者术中、术后和随访期内患者的并发症发生情况.结果 RLRN组患者的术中出血量为(211.41±103.53) mL、手术时间为(212.57±58.53) min、术后进食时间为(56.27±8.33)h以及住院时间为(7.22±2.67)d;ORNRC组患者的术中出血量为(175.61 ±51.22)mL、手术时间为(74.58±11.92) min、术后进食时间为(37.88±10.32)h以及住院时间为(9.38±2.49)d.两组各指标分别比较,差异均有统计学意义(P<0.01).RLRN组患者的术中输血发生率为10.39%,ORNRC组患者术中输血发生率为23.08%,两组比较,差异也有统计学意义(P=0.03).结论 后腹腔镜根治性肾切除术治疗T2期肾癌疗效和安全性均优于开放手术治疗本病,建议临床推广应用. Objective To assess the effectiveness and safety of retroperitoneal laparoscopic radical? nephrectomy (RLRN) and open radical nephrectomies of renal carcinom (ORNRC) for stage T2 renal cancer.Methods A total of 168 patients with stage T2 renal cancer were treated with RLRN and ORNRC respectively.They were divided into two groups:RLRN group (77 cases) and ORNRC group (91 cases) from March 2010 to February 2016 in our hospital.Outcomes measurements included hemorrhage during the surgery period,operation time,time of taking food after surgery,postoperative hospital stay and complications between two groups.Results In the RLRN group,hemorrhage during the surgery period,operation time,time of taking food after surgery,postoperative hospital stay was (211.41 ± 103.53)mL,(212.57 ±58.53)min,(56.27 ±8.33)h and (7.22 ±2.67)d,respectively.In the ORNRC group,the hemorrhage during the surgery period,operation time,time of taking food after surgery,postoperative hospital stay was (175.61 ± 51.22) mL,(74.58 ± 11.92) min,(37.88 ± 10.32) h and (9.38 ± 2.49) d,respectively.Significant differences were found between two groups (P <0.01).The rate of blood transfusion was 10.39% and 23.08% in the RLRN and ORNRC groups,respectively (P =0.03).Conclusions The effectiveness and safety of RLRN are superior to the ORNRC.Thus,it is worthy of clinical application.
作者 谢圣陶 陈广瑜 魏乔红 刘晓彤 焦林 汤尧 Xie Shentao;Chen Guangyu;Wei Qiaohong(Department of Urology,Xi'an Aerospace General Hospital,Xi'an 710100,China)
出处 《国际泌尿系统杂志》 2018年第6期926-928,共3页 International Journal of Urology and Nephrology
关键词 肾肿瘤 肾切除术 腹腔镜检查 Kidney Neoplasms Nephrectomy Laparoscopy
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