摘要
目的 了解镇海区过敏性疾病过敏原的种类分布及流行特征。方法 采用免疫印迹法检测2 149例患者特异性过敏原Ig E抗体（SIg E）和过敏原总Ig E抗体（TIg E）。结果 2 149例患者中过敏原阳性1 435例,阳性率为66. 78%;TIg E阳性1 264例（占58. 82%）; SIg E阳性1 014例（占47. 18%）;吸入性过敏原检出998例,检出率排前3位的SIg E为户尘螨/粉尘螨组合（30. 85%）、猫/狗毛皮屑组合（5. 44%）、霉菌组合1（2. 79%）;食物性过敏原检出930例,检出率排前3位的SIg E为鱼/虾/蟹组合（10. 80%）、牛奶（10. 28%）、牛/羊肉组合（9. 40%）。不同年龄及不同季节过敏原阳性率差异均有统计学意义（χ^2值分别为49. 561、15. 882,P 〈0. 05）。结论 通过分析镇海区过敏原流行病学特点,明确过敏原,避免接触这种物质,减少过敏性疾病的反复发作。
Objective To investigate the distribution and epidemiological characteristics of allergens in allergic diseases in Zhenhai District. Methods The specific allergen IgE antiboby （SIgE） and total IgE antiboby （TIgE） of 2 149 patients were detected by western blot. Results Among the 2 149 patients, 1 435 cases of allergens were detected, with the positive rate of 66.78%. 1 264 cases of TIgEs（58.82% ）, 1 014 cases of SIgEs（47.18% ）, 998 cases of inhaled allergens were detected, the top three SIgEs were house dirt mite/dust mite （30.85%）, cat/dog scurf（5.44% ） and mold combination 1 （2.79%）. 930 cases of food allergens were detected, and the top three SIgEs were fish/shrimp/crab combination（ 10.80% ）, milk（ 10.28% ） and beef/mutton combination（9.40% ）. There differences were statistically significant in the positive rate of allergens at different ages and seasons （χ^2= 49. 561, χ^2= 15. 882, P 〈 0.05）. Conclusion Through analyzing the epidemiological characteris- tics of allergens in Zhenhai District, the allergens were identified to avoid contact with this substance and reduce the recurrence of allergic diseases.
作者
龚敏莉
黄瑛
曹利君
GONG Min-li;HUANG Ying;CAO Li-jun(Clinical Laboratory,the People＇s Hospital of Zhenhai District,Ningbo,Zhejiang 315202,China)
出处
《中国卫生检验杂志》
CAS
2018年第22期2745-2747,共3页
Chinese Journal of Health Laboratory Technology
基金
镇海区医学科技计划项目(2017S101)
